3 Results for "

nitric oxide synthase 2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "nitric oxide synthase 2" in MCE Product Catalog:

9
Isoquercitrin
Isoquercitrin
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9 Cited Publications
Cat. No.: HY-N1445
CAS No.: 482-35-9
Synonyms: Isoquercetin; Quercetin 3-glucoside
Category:  

Apocynaceae Flavonols Flavonoids Phenols Polyphenols Plants  Apocynum venetum Linn. Disease Research Fields Cancer

Target:  

NF-κB NO Synthase

Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
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2
Isoquercitrin (Standard)
Isoquercitrin (Standard)
0 Images
2 Cited Publications
Cat. No.: HY-N1445R
CAS No.: 482-35-9
Synonyms: Isoquercetin (Standard); Quercetin 3-glucoside (Standard)
Category:  

Apocynaceae Flavonols Flavonoids Phenols Polyphenols Plants  Apocynum venetum Linn.

Target:  

Reference Standards NF-κB NO Synthase

Isoquercetin (Standard) is the analytical standard of Isoquercetin. This product is intended for research and analytical applications. Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
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Cucurbitacin R
Cucurbitacin R
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Cat. No.: HY-N11080
CAS No.: 55903-92-9
Category:  

Triterpenes Terpenoids Cucurbitaceae Cayaponia tayuya Plants

Target:  

STAT NF-κB Nuclear Factor of activated T Cells (NFAT) TNF Receptor NO Synthase COX

Cucurbitacin R is an orally active anti-inflammatory agent. Cucurbitacin R is isolated from the roots of Cayaponia tayuya. Cucurbitacin R inhibits Cyclooxygenase-2. Cucurbitacin R inhibits Interleukin-6-induced STAT3 activation and cytokine production, blocks NF-κB activation, and selectively prevents NFAT nuclear translocation without affecting Calcineurin activity. Cucurbitacin R inhibits TNF-α production and Nitric-oxide synthase-2 expression. Cucurbitacin R reduces joint damage, soft tissue swelling, paw edema, ear edema, inflammatory cell infiltration, and epithelial thickness. Cucurbitacin R can be used for research on arthritis and delayed-type hypersensitivity .
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