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nonapeptide peptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (4) Bacterial (4) G Protein-coupled Receptor Kinase (GRK) (1) MDM-2/p53 (1) Melanocortin Receptor (4) MHC (2) Reference Standards (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Endocrinology (2) Infection (4) Metabolic Disease (4) Neurological Disease (2)

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Peptides

Natural
Products

Targets Recommended: RXFP Receptor Formyl Peptide Receptor (FPR) Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) Connective Peptide CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106783

Polymyxin B nonapeptide 2 Publications Verification	Bacterial Antibiotic	Infection
Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .

HY-P5971

TCMCB07 Mifomelatide	Melanocortin Receptor	Neurological Disease Metabolic Disease
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia. TCMCB07 has potential transport capabilities .

HY-P0097

Nonapeptide-1 2 Publications Verification Melanostatine-5	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-P0097A

Nonapeptide-1 acetate salt 2 Publications Verification Melanostatine-5 acetate salt	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 acetate salt is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 acetate salt inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-106783A

Polymyxin B nonapeptide TFA 2 Publications Verification	Bacterial Antibiotic	Infection
Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .

HY-P0303

*Crustacean cardioactive peptide，free acid*	G Protein-coupled Receptor Kinase (GRK)	Cardiovascular Disease Neurological Disease
Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.

HY-P5971A

TCMCB07 TFA	Melanocortin Receptor	Metabolic Disease
TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia .

HY-149988

UNP-6457	MDM-2/p53	Cancer
UNP-6457 is a potent active MDM2-p53 interaction inhibitor with an IC₅₀ values of 8.9 nM .

HY-106783R

Polymyxin B nonapeptide (Standard)	Reference Standards Bacterial Antibiotic	Infection
Polymyxin B nonapeptide (Standard) is the analytical standard of Polymyxin B nonapeptide. This product is intended for research and analytical applications. Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].

HY-106783AR

Polymyxin B nonapeptide TFA (Standard)	Reference Standards Bacterial Antibiotic	Infection
Polymyxin B nonapeptide (TFA) (Standard) is the analytical standard of Polymyxin B nonapeptide (TFA). This product is intended for research and analytical applications. Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].

HY-P11701

SEIDLILGY	MHC	Others
SEIDLILGY is a nonapeptide identified as a peptide ligand derived from mouse major histocompatibility complex class I (MHC). SEIDLILGY serves as a tool chemical stimulant for the specific activation of sensory neurons expressing the particular vomeronasal receptor (V2rf2) .

HY-P11703

TRVLNLGPI	MHC	Others
TRVLNLGPI is an MHC motif-containing, MHC-independent nonapeptide. TRVLNLGPI is not a product of immune presentation, but a product of renal protein degradation, and its concentration is sufficiently high to be specifically recognized by vomeronasal neurons. The concentration of TRVLNLGPI in mouse urine can be six orders of magnitude higher than that of prototype MHC-dependent peptides .

Cat. No.	Product Name	Target	Research Area

HY-106783

Polymyxin B nonapeptide 2 Publications Verification	Bacterial Antibiotic	Infection
Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .

HY-P5971

TCMCB07 Mifomelatide	Melanocortin Receptor	Neurological Disease Metabolic Disease
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia. TCMCB07 has potential transport capabilities .

HY-P0097

Nonapeptide-1 2 Publications Verification Melanostatine-5	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-P0097A

Nonapeptide-1 acetate salt 2 Publications Verification Melanostatine-5 acetate salt	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 acetate salt is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 acetate salt inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-106783A

Polymyxin B nonapeptide TFA 2 Publications Verification	Bacterial Antibiotic	Infection
Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .

HY-P0303

*Crustacean cardioactive peptide，free acid*	G Protein-coupled Receptor Kinase (GRK)	Cardiovascular Disease Neurological Disease
Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.

HY-P5971A

TCMCB07 TFA	Melanocortin Receptor	Metabolic Disease
TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia .

HY-106783R

Polymyxin B nonapeptide (Standard)	Reference Standards Bacterial Antibiotic	Infection
Polymyxin B nonapeptide (Standard) is the analytical standard of Polymyxin B nonapeptide. This product is intended for research and analytical applications. Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].

HY-106783AR

Polymyxin B nonapeptide TFA (Standard)	Reference Standards Bacterial Antibiotic	Infection
Polymyxin B nonapeptide (TFA) (Standard) is the analytical standard of Polymyxin B nonapeptide (TFA). This product is intended for research and analytical applications. Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].

HY-P11701

SEIDLILGY	MHC	Others
SEIDLILGY is a nonapeptide identified as a peptide ligand derived from mouse major histocompatibility complex class I (MHC). SEIDLILGY serves as a tool chemical stimulant for the specific activation of sensory neurons expressing the particular vomeronasal receptor (V2rf2) .

HY-P11703

TRVLNLGPI	MHC	Others
TRVLNLGPI is an MHC motif-containing, MHC-independent nonapeptide. TRVLNLGPI is not a product of immune presentation, but a product of renal protein degradation, and its concentration is sufficiently high to be specifically recognized by vomeronasal neurons. The concentration of TRVLNLGPI in mouse urine can be six orders of magnitude higher than that of prototype MHC-dependent peptides .

*Crustacean cardioactive peptide，free acid*	Cardiovascular Disease Natural Products Animals Neurological Disease Classification of Application Fields Disease Research Fields Source Classification	G Protein-coupled Receptor Kinase (GRK)
Crustacean cardioactive peptide, free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide, free acid also modulates the neuronal activity in other arthropods.

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nonapeptide peptide

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