UNP-6457
UNP-6457 is a potent active MDM2-p53 interaction inhibitor with an IC50 values of 8.9 nM.
For research use only. We do not sell to patients.
- CAS No.: 3072696-60-4
- Formula: C62H71F3N14O10
- Molecular Weight:1229.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 8.9 nM (MDM2-p53) [1]
Chemical Information
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CAS No. 3072696-60-4
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Molecular Weight 1229.31
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Formula C62H71F3N14O10
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SMILES
O=C(C1=CC=CC=C1)N2[C@@]3([H])C[C@@](NC([C@@H](NC([C@H](CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CN4C=C(N=N4)C[C@@H](NC3=O)C(N)=O)=O)C(C)C)=O)CC5=CNC6=CC=CC=C56)=O)CC7=CC=CC=C7)=O)=O)C(C)C)=O)CC8=CC(C(F)(F)F)=CC=C8)=O)([H])C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UNP-6457 Related Classifications
HY-149988 Related Classifications
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