2 Results for "

p53-MDM2 protein-protein interaction

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "p53-MDM2 protein-protein interaction" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P4210
CAS No.: 1451199-98-6
Synonyms: ALRN-6924; MP-4897
Target:  

MDM-2/p53

Research Areas:  

Cancer

Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .
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Cat. No.: HY-130303
CAS No.: 548472-76-0
Target:  

MDM-2/p53

Research Areas:  

Others

Nutlin-2 is an inhibitor of the interaction between p53 and MDM2, with an IC50 of 0.14 μM. Nutlin-2 disrupts the p53-MDM2 protein-protein interaction by occupying the hydrophobic pocket on MDM2 that normally binds to the hydrophobic residues of p53 .
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