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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
pH sensing
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "pH sensing" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: 2-Guanidine-4-methylquinazoline hydrochloride
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GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .
Cat. No.: HY-D0031
CAS No.: 196504-57-1
Synonyms: APTS
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8-Aminopyrene-1,3,6-trisulfonic acid trisodium (APTS) is an anionic fluorescent dye (excitation/emission: 425/503 nm in pH 7.4 PBS). The fluorescence intensity of 8-Aminopyrene-1,3,6-trisulfonic acid trisodium remains stable at pH 4-10. 8-Aminopyrene-1,3,6-trisulfonic acid trisodium retains its fluorescence properties when immobilized in a hydrogel by copolymerization. 8-Aminopyrene-1,3,6-trisulfonic acid trisodium can be used for glucose sensing .
Cat. No.: HY-176550
CAS No.: 1787243-08-6
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ASIC1a antagonist-1 (Compound 5b) is an orthosteric noncompetitive Acid sensing ion channels 1a (ASIC1a) antagonist with an IC50 of 27 nM (pH 6.7). ASIC1a antagonist-1 shifts pH dependence of ASIC1a activation and inhibits its maximal evoked response. ASIC1a antagonist-1 completely inhibits long-term potentiation (LTP) induction in CA3-CA1 pathway. ASIC1a antagonist-1 can be used for brain diseases and pathologies research .
Cat. No.: HY-101005
CAS No.: 16503-22-3
Synonyms: Nα-Methylhistamine dihydrochloride
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N-Methylhistamine dihydrochloride (Nα-Methylhistamine dihydrochloride) is a non-selective Histamine receptor agonist. N-Methylhistamine dihydrochloride activates histamine H1, H2 and H3 receptors; it stimulates central H1 receptors by activating sympathetic α and β adrenergic receptors to inhibit intestinal transit, exerts dose-dependent inhibition on intestinal transit, reduces histamine turnover in mouse brains, and increases gastric acid secretion without altering plasma gastrin concentrations. N-Methylhistamine dihydrochloride produces a pH-dependent, voltage-independent potentiating effect on acid-sensing ion channel 1a, and shows no significant activity toward homologous ASIC2a channels. N-Methylhistamine dihydrochloride can be used in studies related to Helicobacter pylori infection .
Cat. No.: HY-P5172
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Cat. No.: HY-P5780
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Cat. No.: HY-D2992
Cat. No.: HY-D3164
CAS No.: 1380316-56-2
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TPE-Cy is a fluorescent probe with both aggregation-induced emission (AIE) property and pH-dependent luminescent behavior. TPE-Cy exhibits significant luminescent differences under different acidic and alkaline conditions: it shows moderate to strong red emission with linear variation with pH in acidic environments and within the pH range of 5-7, weak or even no emission within the pH range of 7-10, and switches to blue emission under alkaline conditions. TPE-Cy possesses excellent cell permeability and biocompatibility, enabling accurate ratiometric pH sensing and imaging monitoring in living cells via confocal microscopy, ratiometric analysis and flow cytometry .
Cat. No.: HY-D3159
CAS No.: 2304942-78-5
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BTC1070 is an anti-quenching pentamethine cyanine NIR-II fluorescent probe. BTC1070 exhibits high brightness and excellent photostability in aqueous solution (Ex/Em = 1015/1065 nm). BTC1070 can clearly visualize lymphatic structures after intradermal injection, and produces a ratiometric fluorescence response in the acidic range to non-invasively quantify gastric pH. BTC1070 is applicable to studies related to in vivo deep tissue imaging and gastric pH sensing .
Cat. No.: HY-107757R
CAS No.: 5361-15-9
Synonyms: 2-Guanidine-4-methylquinazoline hydrochloride (Standard)
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GMQ hydrochloride (Standard) is the analytical standard of GMQ (hydrochloride) (HY-107757). This product is intended for research and analytical applications. GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .
Cat. No.: HY-D3166
CAS No.: 2413816-64-3
Cat. No.: HY-172754
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
