1 Result for "

pan-HCN-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "pan-HCN-IN-1" in MCE Product Catalog:

Cat. No.: HY-163455
CAS No.: 1334308-63-2
Target:  

HCN Channel

Research Areas:  

Neurological Disease

pan-HCN-IN-1 is a potent HCN ion channel inhibitor with IC50 values of 58 nM, 522 nM, 58 nM, and 58 nM against HCN1, HCN2, HCN3, and HCN4, respectively. pan-HCN-IN-1 exerts voltage-dependent but not use-dependent inhibition, potently inhibits channels in the closed state, and significantly slows the activation time constant of HCN1 currents. pan-HCN-IN-1 can be used for the research of cognitive dysfunction [1].
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