1334308-63-2
1334308-63-2
Chemical Structure
pan-HCN-IN-1
- CAS No.: 1334308-63-2
- Formula:C23H37N3O2
- Molecular Weight:387.56
InChIKey: QQURIRADMQBJKA-UHFFFAOYSA-N
SMILES: CCOC1=CC=CC=C1C(NCC2(CCCCC2)N3CCN(CC3)C(C)C)=O
Biological Activity: pan-HCN-IN-1 (Compound J&J12e) is an inhibitor for hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with IC50 of 58 nM. pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rats brain slices[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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pan-HCN-IN-1 | 99.84% | pan-HCN-IN-1 (Compound J&J12e) is an inhibitor for hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with IC50 of 58 nM. pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rats brain slices. | ||||||||||||||||||||
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References
Keywords
