phosphoramidite reagents

By Targets:	DNA Stain (4) DNA/RNA Synthesis (2) Fluorescent Dye (5) Nucleoside Antimetabolite/Analog (4) Phosphoramidites (9) PROTAC Linkers (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Infection (1)
Click Chemistry:	PROTAC Synthesis (2) Alkynes (2)
Oligonucleotides:	Fluorescent Dye Phosphoramidite (1) Adenine (1) Cytosine (1) Uracil (5) Other Phosphoramidite (1) Phosphoramidites (9)

Targets Recommended: Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008849

DMT-dC(bz) Phosphoramidite	Phosphoramidites DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
DMT-dC (bz) Phosphoramidite is a protected deoxycytidine phosphoramidite monomer, as well as a building block for mechanochemical DNA synthesis. DMT-dC (bz) Phosphoramidite serves as a reagent for oligonucleotide synthesis .

HY-D1090

JOE	DNA Stain Fluorescent Dye	Others
JOE is a xanthene fluorophore (i.e., 4′,5′-dichloro-2′,7′-dimethoxy-5 (6)-carboxyfluorescein; 2',7'-dimethoxy-4',5'-dichloro-6-carboxyfluorescein) with an absorption wavelength of approximately 525 nm and an emission wavelength of approximately 550 nm. The fluorescence quantum yield of JOE correlates with the rigidity of the linker arm and the distance to dG nucleoside. JOE is commonly used as a fluorescent label for oligonucleotides and molecular beacon probes, and also serves as the acceptor fluorophore in fluorescence energy transfer primers for DNA sequencing .

HY-151651

Hexaethylene glycol phosphoramidite Spacer phosphoramidite 18	Phosphoramidites	Others
Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amidite reagent for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite can be used as a linker in synthesis of nucleotide chain and qPCR probes .

HY-148947

Cy5 Phosphoramidite	Fluorescent Dye Phosphoramidites	Others
Cy5 Phosphoramidite is a fluorescent labeling reagent . Cy5 Phosphoramidite serves as a fluorescent tag for 3' terminal labeling of single-stranded DNA, enabling fluorescence-based nucleic acid detection, monitoring, quantification, and in vitro study .

HY-D2245

Cy5.5 phosphoramidite	Fluorescent Dye	Others
Cy5.5 phosphoramidite, a cyanine derivative, is a fluorescent labeling reagent for preparing fluorescence-labeled oligonucleotides .

HY-145340

2'-O-Propargyl A(Bz)-3'-phosphoramidite	Nucleoside Antimetabolite/Analog Phosphoramidites	Cancer
2'-O-Propargyl A(Bz)-3'-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . 2'-O-Propargyl A(Bz)-3'-phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151750

Pyrene phosphoramidite dU	Fluorescent Dye Phosphoramidites Nucleoside Antimetabolite/Analog	Others
Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.

HY-D1409

DMTr-4'-F-U-CED-TBDMS phosphoramidite DMTr-4'-F-uridine-CED-TBDMS phosphoramidite	DNA Stain Phosphoramidites	Cardiovascular Disease
DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-W096141

Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite	PROTAC Linkers	Cancer
Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1410

DMTr-4'-F-5-Me-U-CED phosphoramidite DMTr-4'-F-5-Methyluridine-CED phosphoramidite	Fluorescent Dye Phosphoramidites	Others
DMTr-4'-F-5-Me-U-CED phosphoramidite (DMTr-4'-F-5-Methyluridine-CED phosphoramidite), a dye reagent for oligonucleotide labeling, acts as efficient as the incorporation of native deoxyribonucleoside phosphoramidites. DMTr-4'-F-5-Me-U-CED phosphoramidite is a building block .

HY-D1408

DMTr-4'-Me-U-CED-TBDMS phosphoramidite DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite	DNA Stain Phosphoramidites	Cardiovascular Disease
DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-D1411

DMTr-4'-CF3-5-Me-U-CED phosphoramidite DMTr-4'-CF3-5-Methyluridine-CED phosphoramidite	DNA Stain Phosphoramidites	Others
DMTr-4'-CF3-5-Me-U-CED phosphoramidite (DMTr-4'-CF3-5-Methyluridine-CED phosphoramidite), the modified oligodeoxynucleotide (ODN), is a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA research .

HY-W096140

Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite	PROTAC Linkers	Cancer
Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W1119956

5’-(E)-VPG Phosphoramidite 5'(E)-VP-2'-OMe-iBu-G phosphoramidite	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Infection
5'-(E)-VPG Phosphoramidite (5'(E)-VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research .

Cat. No.	Product Name	Type

HY-D1090

JOE	Fluorescent Dyes
JOE is a xanthene fluorophore (i.e., 4′,5′-dichloro-2′,7′-dimethoxy-5 (6)-carboxyfluorescein; 2',7'-dimethoxy-4',5'-dichloro-6-carboxyfluorescein) with an absorption wavelength of approximately 525 nm and an emission wavelength of approximately 550 nm. The fluorescence quantum yield of JOE correlates with the rigidity of the linker arm and the distance to dG nucleoside. JOE is commonly used as a fluorescent label for oligonucleotides and molecular beacon probes, and also serves as the acceptor fluorophore in fluorescence energy transfer primers for DNA sequencing .

JOE

Fluorescent Dyes

JOE is a xanthene fluorophore (i.e., 4′,5′-dichloro-2′,7′-dimethoxy-5 (6)-carboxyfluorescein; 2',7'-dimethoxy-4',5'-dichloro-6-carboxyfluorescein) with an absorption wavelength of approximately 525 nm and an emission wavelength of approximately 550 nm. The fluorescence quantum yield of JOE correlates with the rigidity of the linker arm and the distance to dG nucleoside. JOE is commonly used as a fluorescent label for oligonucleotides and molecular beacon probes, and also serves as the acceptor fluorophore in fluorescence energy transfer primers for DNA sequencing .

HY-D2245

Cy5.5 phosphoramidite	Fluorescent Dyes
Cy5.5 phosphoramidite, a cyanine derivative, is a fluorescent labeling reagent for preparing fluorescence-labeled oligonucleotides .

HY-151750

Pyrene phosphoramidite dU	Fluorescent Dyes
Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.

HY-D1409

DMTr-4'-F-U-CED-TBDMS phosphoramidite DMTr-4'-F-uridine-CED-TBDMS phosphoramidite	Fluorescent Dyes
DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-D1410

DMTr-4'-F-5-Me-U-CED phosphoramidite DMTr-4'-F-5-Methyluridine-CED phosphoramidite	Fluorescent Dyes
DMTr-4'-F-5-Me-U-CED phosphoramidite (DMTr-4'-F-5-Methyluridine-CED phosphoramidite), a dye reagent for oligonucleotide labeling, acts as efficient as the incorporation of native deoxyribonucleoside phosphoramidites. DMTr-4'-F-5-Me-U-CED phosphoramidite is a building block .

HY-D1408

DMTr-4'-Me-U-CED-TBDMS phosphoramidite DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite	Fluorescent Dyes
DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

Cat. No.	Product Name	Type

HY-W008849

DMT-dC(bz) Phosphoramidite	Biochemical Assay Reagents
DMT-dC (bz) Phosphoramidite is a protected deoxycytidine phosphoramidite monomer, as well as a building block for mechanochemical DNA synthesis. DMT-dC (bz) Phosphoramidite serves as a reagent for oligonucleotide synthesis .

Cat. No.	Product Name		Classification

HY-W096141

Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite		Alkynes PROTAC Synthesis
Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W096140

Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite		Alkynes PROTAC Synthesis
Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W008849

DMT-dC(bz) Phosphoramidite		Phosphoramidites Cytosine
DMT-dC (bz) Phosphoramidite is a protected deoxycytidine phosphoramidite monomer, as well as a building block for mechanochemical DNA synthesis. DMT-dC (bz) Phosphoramidite serves as a reagent for oligonucleotide synthesis .

HY-151651

Hexaethylene glycol phosphoramidite Spacer phosphoramidite 18		Phosphoramidites Other Phosphoramidite
Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amidite reagent for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite can be used as a linker in synthesis of nucleotide chain and qPCR probes .

HY-148947

Cy5 Phosphoramidite		Phosphoramidites Fluorescent Dye Phosphoramidite
Cy5 Phosphoramidite is a fluorescent labeling reagent . Cy5 Phosphoramidite serves as a fluorescent tag for 3' terminal labeling of single-stranded DNA, enabling fluorescence-based nucleic acid detection, monitoring, quantification, and in vitro study .

HY-145340

2'-O-Propargyl A(Bz)-3'-phosphoramidite		Phosphoramidites Adenine
2'-O-Propargyl A(Bz)-3'-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . 2'-O-Propargyl A(Bz)-3'-phosphoramidite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151750

Pyrene phosphoramidite dU		Phosphoramidites Uracil
Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.

HY-D1409

DMTr-4'-F-U-CED-TBDMS phosphoramidite DMTr-4'-F-uridine-CED-TBDMS phosphoramidite		Phosphoramidites Uracil
DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-D1410

DMTr-4'-F-5-Me-U-CED phosphoramidite DMTr-4'-F-5-Methyluridine-CED phosphoramidite		Phosphoramidites Uracil
DMTr-4'-F-5-Me-U-CED phosphoramidite (DMTr-4'-F-5-Methyluridine-CED phosphoramidite), a dye reagent for oligonucleotide labeling, acts as efficient as the incorporation of native deoxyribonucleoside phosphoramidites. DMTr-4'-F-5-Me-U-CED phosphoramidite is a building block .

HY-D1408

DMTr-4'-Me-U-CED-TBDMS phosphoramidite DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite		Phosphoramidites Uracil
DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-D1411

DMTr-4'-CF3-5-Me-U-CED phosphoramidite DMTr-4'-CF3-5-Methyluridine-CED phosphoramidite		Phosphoramidites Uracil
DMTr-4'-CF3-5-Me-U-CED phosphoramidite (DMTr-4'-CF3-5-Methyluridine-CED phosphoramidite), the modified oligodeoxynucleotide (ODN), is a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA research .

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Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Click Chemistry

Oligonucleotides