182873-67-2
Chemical Structure
Cy5 Phosphoramidite
- CAS No.: 182873-67-2
- Formula:C60H72ClN4O4P
- Molecular Weight:979.66
IUPAC Name: 2-((1E,3E)-5-((E)-1-(3-(((2-cyanoethoxy)(diisopropylamino)phosphanyl)oxy)propyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1-(3-((4-methoxyphenyl)diphenylmethoxy)propyl)-3,3-dimethyl-3H-indol-1-ium chloride
InChIKey: GWCNEDQILVVBDJ-UHFFFAOYSA-M
SMILES: N#CCCOP(N(C(C)C)C(C)C)OCCCN1C2=C(C(C)(C)/C1=C\C=C\C=C\C3=[N+](CCCOC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)C7=C(C3(C)C)C=CC=C7)C=CC=C2.[Cl-]
Biological Activity: Cy5 Phosphoramidite is a fluorescent labeling reagent. Cy5 Phosphoramidite serves as a fluorescent tag for 3' terminal labeling of single-stranded DNA, enabling fluorescence-based nucleic acid detection, monitoring, quantification, and in vitro study[1][2].
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Cy5 Phosphoramidite | Cy5 Phosphoramidite is a fluorescent labeling reagent. Cy5 Phosphoramidite serves as a fluorescent tag for 3' terminal labeling of single-stranded DNA, enabling fluorescence-based nucleic acid detection, monitoring, quantification, and in vitro study. | |||||||||||||||||||||
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- [1]. Meares A, et al. Synthesis of Substituted Cy5 Phosphoramidite Derivatives and Their Incorporation into Oligonucleotides Using Automated DNA Synthesis. ACS Omega. 2022;7(13):11002-11016. Published 2022 Mar 22. [Content Brief]
- [2]. Kekić T, et al. Sequence-dependence of Cy3 and Cy5 dyes in 3' terminally-labeled single-stranded DNA. Sci Rep. 2022;12(1):14803. Published 2022 Aug 31. [Content Brief]
Keywords