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Results for "

phytotoxic activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (8) DNA/RNA Synthesis (2) Drug Derivative (1) Endogenous Metabolite (3) Environmental Pollutants (4) Fungal (10) Herbicide (6) HIF/HIF Prolyl-Hydroxylase (1) HIV (1) HPPD (2) Lipoxygenase (1) Parasite (3) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Reverse Transcriptase (1) TGF-β Receptor (1) Topoisomerase (1)
By Research Areas:	Cancer (7) Infection (19)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19828

Herboxidiene GEX1A	DNA/RNA Synthesis	Cancer
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .

HY-137910

Tembotrione	Environmental Pollutants HPPD Herbicide	Infection
Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy .

HY-128467

Dehydroacetic acid sodium Sodium dehydroacetate	Environmental Pollutants Fungal Bacterial	Infection
Dehydroacetic acid sodium, a pyrone derivative acts as an antibacterial and antifungal agent. Dehydroacetic acid possess phytotoxic activity .

HY-N3270

Methyl orsellinate	Fungal Lipoxygenase	Infection
Methyl orsellinate is a phytotoxic compound with antifungal activities. Methyl orsellinate is a 5-lipoxygenase inhibitor with an IC₅₀ value of 59.6 μM. Methyl orsellinate can be used for fungal infection research .

HY-B1211

Dehydroacetic acid Biocide 470F	Environmental Pollutants Bacterial Fungal	Infection
Dehydroacetic acid (Biocide 470F) is a pyrone derivative. Dehydroacetic acid has antibacterial, antifungal and phytotoxic activities. Dehydroacetic acid can be added to cosmetics, food and beverages for preservation and other purposes. Dehydroacetic acid can also be used to synthesize various heterocycles and cycloaddition products .

HY-136376

Mefenpyr-diethyl	Environmental Pollutants Herbicide	Others
Mefenpyr-diethyl is a pyrazoline-type herbicide safener that functions to enhance lipid biosynthesis. Mefenpyr-diethyl effectively prevents herbicide-induced phytotoxic damage caused by herbicides such as fenoxaprop-p-ethyl (HY-B2013) and mesosulfuron-methyl (HY-126987) by protecting cereal crops including wheat. Mefenpyr-diethyl significantly increases lipid content in wheat either when applied alone or in combination with the herbicide fenoxaprop-p-ethyl. The mechanism of action of Mefenpyr-diethyl does not involve the induction of glutathione S-transferase (GST) activity in wheat .

HY-N8349

19,20-Epoxycytochalasin D	Parasite Endogenous Metabolite	Infection Cancer
19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity .

HY-N15497

Terpestacin	Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase	Cancer
Terpestacin is found in Phoma exigua var. heteromorpha. Terpestacin binds to UQCRB to inhibit the production of mitochondrial ROS and HIF-1α. Terpestacin inhibits tumor angiogenesis in the FM3A breast cancer cell xenograft mouse model. Terpestacin has antitumor activity and phytotoxicity .

HY-113604

Pentabromopseudilin	TGF-β Receptor	Cancer
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer .

HY-108988

Albicidin	Antibiotic Bacterial Topoisomerase DNA/RNA Synthesis	Infection
Albicidin is a peptide antibiotic with phytotoxic activity. Albicidin potently inhibits bacterial and plant DNA gyrase at nanomolar concentrations, blocks DNA replication, and exhibits excellent antibacterial efficacy against multidrug-resistant bacteria. Albicidin possesses bactericidal activity against Gram-positive and Gram-negative microorganisms, and acts as a virulence factor for the systemic plant infection by Xanthomonas albilineans. Albicidin can be used in studies related to bacterial infections and sugarcane leaf blight .

HY-W751002

Orthosporin (+)-Orthosporin	Endogenous Metabolite Bacterial HIV Reverse Transcriptase	Infection
Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity .

HY-114319

β-Cembrenediol	Others	Cancer
β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation. β-Cembrenediol decreases the protein expression of TDO2, IDO1. β-Cembrenediol has the potential for the research of prostate cancer .

HY-138100

Hyalodendrin (+)-Hyalodendrin	Fungal	Infection
Hyalodendrin ((+)-Hyalodendrin) is a fungal growth inhibitor with inhibitory activity against wood decay fungi. Hyalodendrin has low phytotoxicity, with an acute toxicity (LD50) of 75 mg/kg in mice .

HY-N10260

Curvulinic acid	Others	Others
Curvulinic acid is a phytotoxic compound, has herbicidal activity .

HY-N9207

Germanicol acetate	Others	Others
Germanicol acetate can be extracted from Euphorbia heterophylla L. and has phytotoxic activity .

HY-N8385

19,20-Epoxycytochalasin C	Parasite Endogenous Metabolite	Infection Cancer
19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity .

HY-N13889

Altiloxin A	Fungal	Infection
Altiloxin A, a fungal metabolite, is a drimane-type sesquiterpenoid. Altiloxin A shows phytotoxic activity on the lettuce seedlings .

HY-128467R

Dehydroacetic acid sodium (Standard) Sodium dehydroacetate (Standard)	Reference Standards Bacterial Fungal	Infection
Dehydroacetic acid (sodium) (Standard) is the analytical standard of Dehydroacetic acid (sodium). This product is intended for research and analytical applications. Dehydroacetic acid sodium, a pyrone derivative acts as an antibacterial and antifungal agent. Dehydroacetic acid possess phytotoxic activity .

HY-N6731

Hydrolyzed Fumonisin B2	Others	Infection
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. Hydrolyzed Fumonisin B2 (HFB2) exhibits phytotoxicity .

HY-125461

Altersolanol A Stemphylin; NSC 173943	Bacterial	Infection
Altersolanol A (Stemphylin; NSC 173943) exhibits antimicrobial activities against Bacillus subtilis and Pseudomonas aeruginosa, with MIC of 25-100 μg/mL. Altersolanol A exhibits no phytotoxicity to Taxus (at dose of 4 μg/μL) .

HY-125698

3-Deoxyaphidicolin	Parasite	Infection
3-Deoxyaphidicolin exhibits phytotoxic efficacy, that inhibits root growth of lettuce seedlings. 3-Deoxyaphidicolin also exhibits leishmanicidal activity against Leishmania major and Leishmania braziliensis .

HY-N10267

Carviolin	Fungal	Infection
Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities .

HY-B1211R

Dehydroacetic acid (Standard) Biocide 470F (Standard)	Reference Standards Bacterial Fungal	Infection
Dehydroacetic acid (Standard) (Biocide 470F (Standard)) is the analytical standard of Dehydroacetic acid (HY-B1211). This product is intended for research and analytical applications. Dehydroacetic acid (Biocide 470F) is a pyrone derivative. Dehydroacetic acid has antibacterial, antifungal and phytotoxic activities. Dehydroacetic acid can be added to cosmetics, food and beverages for preservation and other purposes. Dehydroacetic acid can also be used to synthesize various heterocycles and cycloaddition products .

HY-137910R

Tembotrione (Standard)	Reference Standards Herbicide HPPD	Others
Tembotrione (Standard) is the analytical standard of Tembotrione. This product is intended for research and analytical applications. Tembotrione is a drug that may reduce the productivity of carrots. Tembotrione has the activity of reducing carrot stem mass. Tembotrione can be used to study the total productivity of carrot . Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy .

HY-N14066

Ascochitine	Fungal	Infection
Ascochitine, a polyketide-derived secondary metabolite, is a selective antifungal agent. Ascochitine exhibits broad-spectrum phytotoxicity and antimicrobial activities .

HY-N16432

Nidulol	Fungal	Infection
Nidulol is a compound that can be isolated from the fungus Aspergillus nidulans metabolites. Nidulol shows no phytotoxic activity against Zea mays and Medicago polymorpha L. at a concentration of 5 mM .

HY-N15185

Pyrenophorin (-)-Pyrenophorin	Herbicide	Cancer
Pyrenophorin ((-)-Pyrenophorin) is a fungal metabolite that has been found in D. avenae and has phytotoxic activity. Pyrenophorin shows strong cytotoxicity against several cancer cell lines with IC₅₀ values ranging from 0.07 to 7.8 μM .

HY-N9715

4-Chloropinselin	Herbicide	Others
4-Chloropinselin is a chlorine-containing xanthone herbicide that can be isolated from Alternaria sonchi. 4-Chloropinselin is a biosynthetic precursor or degradation product of chloromonilicin and exhibits phytotoxic and antimicrobial activity. 4-Chloropinselin can inhibit the growth of weeds such as field sowthistle and suppress the proliferation of certain microorganisms .

HY-119633

Perfluidone	Herbicide	Others
Perfluidone is a selective 3-ketoacyl-CoA synthase (KCS) inhibitor with IC₅₀s of 0.21 and 7.60 μM for CER6 (KCS6) and FAE1 (KCS18), respectively. Perfluidone significantly inhibits very-long-chain fatty acid (VLCFA) synthesis. Perfluidone has phytotoxic activity and inhibits Lemna paucicostata growth. Perfluidone can be uses as a plant growth regulator and herbicide for agriculture research .

HY-W748468

6-Isopentenyloxyisobergapten	Drug Derivative Bacterial	Infection
6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC₅₀ of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC₅₀ of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM .

Herboxidiene GEX1A	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Biological Pesticide Research Cancer Agricultural Research Source Classification	DNA/RNA Synthesis
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .

Methyl orsellinate	Natural Products Rhododendron primuliflorum Bureau & Franch. Plants Ericaceae Source Classification	Fungal Lipoxygenase
Methyl orsellinate is a phytotoxic compound with antifungal activities. Methyl orsellinate is a 5-lipoxygenase inhibitor with an IC₅₀ value of 59.6 μM. Methyl orsellinate can be used for fungal infection research .

19,20-Epoxycytochalasin D	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite Endogenous Metabolite
19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity .

Terpestacin	Animals Terpenoids Sesquiterpenes Source Classification	Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase
Terpestacin is found in Phoma exigua var. heteromorpha. Terpestacin binds to UQCRB to inhibit the production of mitochondrial ROS and HIF-1α. Terpestacin inhibits tumor angiogenesis in the FM3A breast cancer cell xenograft mouse model. Terpestacin has antitumor activity and phytotoxicity .

Pentabromopseudilin	Natural Products Marine natural products Marine microorganism Source Classification	TGF-β Receptor
Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour and phytotoxic activities. PBrP is a reversible and allosteric inhibitor of myosin Va (MyoVa). PBrP also is a potent inhibitor of transforming growth factor-β (TGF-β) activity. PBrP can be used for the research of fibrotic diseases and cancer .

Orthosporin (+)-Orthosporin	Structural Classification Microorganisms Coumarins Phenylpropanoids Source Classification	Endogenous Metabolite Bacterial HIV Reverse Transcriptase
Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity .

β-Cembrenediol	Nicotiana tabacum L. Terpenoids Diterpenoids Solanaceae Plants Source Classification	Others
β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation. β-Cembrenediol decreases the protein expression of TDO2, IDO1. β-Cembrenediol has the potential for the research of prostate cancer .

Hyalodendrin (+)-Hyalodendrin	Microorganisms Antibiotics Other Antibiotics Source Classification	Fungal
Hyalodendrin ((+)-Hyalodendrin) is a fungal growth inhibitor with inhibitory activity against wood decay fungi. Hyalodendrin has low phytotoxicity, with an acute toxicity (LD50) of 75 mg/kg in mice .

Curvulinic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Disease Research Fields Biological Pesticide Research Agricultural Research Source Classification	Others
Curvulinic acid is a phytotoxic compound, has herbicidal activity .

Germanicol acetate	Triterpenes Terpenoids Euphorbiaceae Plants Euphorbia heterophylla L. Source Classification	Others
Germanicol acetate can be extracted from Euphorbia heterophylla L. and has phytotoxic activity .

19,20-Epoxycytochalasin C	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite Endogenous Metabolite
19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity .

Altiloxin A	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source Classification	Fungal
Altiloxin A, a fungal metabolite, is a drimane-type sesquiterpenoid. Altiloxin A shows phytotoxic activity on the lettuce seedlings .

Hydrolyzed Fumonisin B2	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Others
Hydrolyzed Fumonisin B2 (HFB2) is a hydrolysis product of fumonisins (HF), which retains biological activity. Hydrolyzed Fumonisin B2 (HFB2) exhibits phytotoxicity .

Altersolanol A Stemphylin; NSC 173943	Quinones Taxaceae Benzene Quinones Plants Taxus wallichiana Zucc. Source Classification	Bacterial
Altersolanol A (Stemphylin; NSC 173943) exhibits antimicrobial activities against Bacillus subtilis and Pseudomonas aeruginosa, with MIC of 25-100 μg/mL. Altersolanol A exhibits no phytotoxicity to Taxus (at dose of 4 μg/μL) .

3-Deoxyaphidicolin	Natural Products Microorganisms Source Classification	Parasite
3-Deoxyaphidicolin exhibits phytotoxic efficacy, that inhibits root growth of lettuce seedlings. 3-Deoxyaphidicolin also exhibits leishmanicidal activity against Leishmania major and Leishmania braziliensis .

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phytotoxic activity

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Natural
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