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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
platelet adhesion
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "platelet adhesion" in MCE Product Catalog:
3
3 Cited Publications
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TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .
3
3 Cited Publications
Cat. No.: HY-P80447
Synonyms: adhesion molecule antibody;
CD31 antibody;
CD31 antigen antibody;
CD31 EndoCAM antibody;
EndoCAM antibody;
FLJ34100 antibody;
FLJ58394 antibody;
GPIIA antibody;
GPIIA' antibody;
PECA1 antibody;
PECA1_HUMAN antibody;
Pecam 1 antibody;
PECAM 1 CD31 EndoCAM antibody;
PECAM antibody;
PECAM-1 antibody;
Pecam1 antibody;
platelet and endothelial cell adhesion molecule 1 antibody;
platelet endothelial cell adhesion molecule antibody;
platelet/endothelial cell adhesion molecule 1 antibody;
2
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2
2 Cited Publications
Cat. No.: HY-160109
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Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
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1
1 Cited Publications
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BTT-3033 is an orally active conformation-selective inhibitor of α2β1 (EC50: 130 nM) by binding to the α2I domain. BTT-3033 inhibits platelet binding to collagen I and cell proliferation, and induces cell apoptosis. BTT-3033 can be used in the research of prostate cancer, inflammation and cardiovascular disease .
1
1 Cited Publications
Cat. No.: HY-B0683
CAS No.: 74397-12-9
Synonyms: 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206
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Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .
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1
1 Cited Publications
Cat. No.: HY-P1741
CAS No.: 137235-80-4
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1
Category:
Metabolic Disease Plants Etunia hybrida (J. D. Hooker) Vilmorin Anthocyans Flavonoids Microorganisms Phenols Polyphenols Solanaceae Disease Research Fields
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1
1 Cited Publications
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1
1 Cited Publications
Cat. No.: HY-P99121
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1
1 Cited Publications
Cat. No.: HY-P1741A
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1
1
1
Cat. No.: HY-112624B
CAS No.: 9004-54-0
Synonyms: Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
Cat. No.: HY-N2163
CAS No.: 172760-03-1
Category:
Other Monoterpenes other families Monophenols Terpenoids Other Diseases Phenols Plants Disease Research Fields
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Cat. No.: HY-138053
CAS No.: 90831-71-3
Synonyms: Ristomycin III
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Ristocetin A sulfate (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor (VWF) and bacterial cell wall components. Ristocetin A sulfate interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation, Ristocetin A sulfate drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A sulfate not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A sulfate is widely used in studies related to thromboembolic diseases and bacterial infections .
Cat. No.: HY-P5322
CAS No.: 138849-26-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
