137235-80-4
Chemical Structure
Fibrinogen-Binding Peptide
- CAS No.: 137235-80-4
- Formula:C25H39N7O8
- Molecular Weight:565.62
IUPAC Name: (S)-4-amino-5-(((S)-1-(((2S,3S)-1-((S)-2-(((S)-1-carboxyethyl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxopentan-2-yl)amino)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
InChIKey: VWJLJHZPMZGDDV-HOCDWTQPSA-N
SMILES: C[C@@H](C(O)=O)NC([C@H]1N(C([C@H]([C@@H](C)CC)NC([C@H](CC2=CNC=N2)NC([C@H](CCC(O)=O)N)=O)=O)=O)CCC1)=O
Biological Activity: Fibrinogen-Binding Peptide is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide can be used for research on thrombosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fibrinogen-Binding Peptide | 96.32% | Fibrinogen-Binding Peptide is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide can be used for research on thrombosis. | ||||||||||||||||||||
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References
- [1]. Gartner TK, et al. The peptide Glu-His-Ile-Pro-Ala binds fibrinogen and inhibits platelet aggregation and adhesion to fibrinogen and vitronectin. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1991 Oct;198(1):649-55. [Content Brief]
- [2]. Gartner TK, et al. The peptides APLHK, EHIPA and GAPL are hydropathically equivalent peptide mimics of a fibrinogen binding domain of glycoprotein IIb/IIIa. Biochemical and biophysical research communications. 1991 Nov 14;180(3):1446-52. [Content Brief]
