2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. RS 09

RS09 is a LPS peptide mimic serves as a candidate to be considered as a new class of TLR4 agonist adjuvant. RS09 increases antibody production in a vaccine setting.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

RS 09 Chemical Structure

RS 09 Chemical Structure

CAS No. : 1449566-36-2

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1 mg USD 50 In-stock
5 mg USD 120 In-stock
10 mg USD 190 In-stock
25 mg USD 350 In-stock
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Based on 3 publication(s) in Google Scholar

Other Forms of RS 09:

RS 09 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

RS09 is a LPS peptide mimic serves as a candidate to be considered as a new class of TLR4 agonist adjuvant. RS09 increases antibody production in a vaccine setting[1].

Molecular Weight

691.78

Formula

C31H49N9O9
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

APPHALS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (144.55 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4455 mL 7.2277 mL 14.4555 mL
5 mM 0.2891 mL 1.4455 mL 2.8911 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (144.55 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4455 mL 7.2277 mL 14.4555 mL 36.1387 mL
5 mM 0.2891 mL 1.4455 mL 2.8911 mL 7.2277 mL
10 mM 0.1446 mL 0.7228 mL 1.4455 mL 3.6139 mL
15 mM 0.0964 mL 0.4818 mL 0.9637 mL 2.4092 mL
20 mM 0.0723 mL 0.3614 mL 0.7228 mL 1.8069 mL
25 mM 0.0578 mL 0.2891 mL 0.5782 mL 1.4455 mL
30 mM 0.0482 mL 0.2409 mL 0.4818 mL 1.2046 mL
40 mM 0.0361 mL 0.1807 mL 0.3614 mL 0.9035 mL
50 mM 0.0289 mL 0.1446 mL 0.2891 mL 0.7228 mL
60 mM 0.0241 mL 0.1205 mL 0.2409 mL 0.6023 mL
80 mM 0.0181 mL 0.0903 mL 0.1807 mL 0.4517 mL
100 mM 0.0145 mL 0.0723 mL 0.1446 mL 0.3614 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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RS 09 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RS 091449566-36-2RS09RS-09Toll-like Receptor (TLR)LPSpeptidemimicTLR4vaccineInhibitorinhibitorinhibit

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