1. Cytoskeleton
  2. Integrin
  3. TC-I 15

TC-I 15 

Cat. No.: HY-107588 Purity: 99.80%
COA Handling Instructions

TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition.

For research use only. We do not sell to patients.

TC-I 15 Chemical Structure

TC-I 15 Chemical Structure

CAS No. : 916734-43-5

Size Price Stock Quantity
5 mg USD 220 In-stock
Estimated Time of Arrival: December 31
10 mg USD 380 In-stock
Estimated Time of Arrival: December 31
25 mg USD 810 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1300 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition[1].

IC50 & Target

α2β1

0.4 (α2β1 μM (IC50)

α2β1

26.8 (α2β1 μM (IC50)

α1β1

23.6 (α1β1 μM (IC50)

α1β1

24.4 (α1β1 μM (IC50)

α11β1

177 (α11β1 μM (IC50)

α11β1

3177 (α11β μM (IC50)

Molecular Weight

520.62

Formula

C23H28N4O6S2

CAS No.
SMILES

O=[S](N(CSC(C)1C)[[email protected]@H]1C(N[[email protected]](C(O)=O)CNC(NCC2=CC=CC=C2)=O)=O)(C3=CC=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (480.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9208 mL 9.6039 mL 19.2079 mL
5 mM 0.3842 mL 1.9208 mL 3.8416 mL
10 mM 0.1921 mL 0.9604 mL 1.9208 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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TC-I 15
Cat. No.:
HY-107588
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