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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
protein thermal stability
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "protein thermal stability" in MCE Product Catalog:
Cat. No.: HY-W020780
CAS No.: 724722-89-8
Synonyms: mPEG5000-Maleimide
Cat. No.: HY-D2001
CAS No.: 863772-22-9
Synonyms: (R)-VX-445
Target:
Research Areas:
(R)-Elexacaftor ((R)-VX-445) is the enantiomer of Elexacaftor (HY-111772). Elexacaftor is an orally active CFTR modulator that targets nucleotide-binding domain 1. Elexacaftor stabilizes misfolded F508del-CFTR protein, enhances its trafficking to the plasma membrane, and significantly improves metabolic stability, thermal stability and ion conductivity. Elexacaftor not only restores chloride transport function in nasal epithelial cells and rescues multiple CFTR mutation subtypes, but also exerts multiplicative synergistic effects with Ivacaftor (HY-13017), and is often used in a triple combination therapy with Tezacaftor (HY-15448). Elexacaftor is widely used in basic and clinical translational research on cystic fibrosis .
Cat. No.: HY-D2001A
Cat. No.: HY-D1959
CAS No.: 1443553-12-5
Cat. No.: HY-170933
CAS No.: 3046378-98-4
SGK1-IN-6 is a selective SGK1 inhibitor with an IC50 of 0.39 μM, showing selectivity over SGK2/3. SGK1-IN-6 inhibits cancer cell migration and invasion, improves SGK1 protein thermal stability. SGK1-IN-6 decreases SGK1 protein levels in tumor tissues, suppresses tumor growth in mouse xenograft models. SGK1-IN-6 can be used for the research of prostate cancer .
Cat. No.: HY-153524
CAS No.: 892156-28-4
Cat. No.: HY-D1935
CAS No.: 1173020-88-6
Cat. No.: HY-D1957
CAS No.: 2982226-58-2
Cat. No.: HY-D2016
Cat. No.: HY-D2019
CAS No.: 1005770-00-2
Cat. No.: HY-D2021
CAS No.: 870534-97-7
Cat. No.: HY-D2046
CAS No.: 924660-19-5
Cat. No.: HY-D2073
CAS No.: 1537182-26-5
Cat. No.: HY-152469
CAS No.: 2894121-68-5
Target:
Research Areas:
Eleven-Nineteen-Leukemia Protein IN-1 is an inhibitor of ENL YEATS domain with an IC50 value of 14.5 nM. Eleven-Nineteen-Leukemia Protein IN-1 interacts with ENL protein and enhances the thermal stability of ENL protein in vitro .
Cat. No.: HY-152471
CAS No.: 2894121-83-4
Target:
Research Areas:
Eleven-Nineteen-Leukemia Protein IN-3 is an orally active inhibitor of ENL YEATS domain with an IC50 value of 15.4 nM. Eleven-Nineteen-Leukemia Protein IN-3 down-regulates MYC expression through ENL in cells and can enhances the thermal stability of ENL protein in vitro .
Cat. No.: HY-D1917
CAS No.: 914203-48-8
Cat. No.: HY-D1929
Cat. No.: HY-D1932
CAS No.: 670269-33-7
Cat. No.: HY-D1933
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
