2894121-68-5
2894121-68-5
Chemical Structure
Eleven-Nineteen-Leukemia Protein IN-1
- CAS No.: 2894121-68-5
- Formula:C27H33N7O2
- Molecular Weight:487.60
IUPAC Name: (S)-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazol-5-yl)-1-(2-morpholinoethyl)-1H-indazole-5-carboxamide
InChIKey: MVKGWIMIIHYNGU-IBGZPJMESA-N
SMILES: C[C@H]1CCCN1CC2=NC3=CC(NC(C4=CC5=C(N(N=C5)CCN6CCOCC6)C=C4)=O)=CC=C3N2
Biological Activity: Eleven-Nineteen-Leukemia Protein IN-1 is an inhibitor of ENL YEATS domain with an IC50 value of 14.5 nM. Eleven-Nineteen-Leukemia Protein IN-1 interacts with ENL protein and enhances the thermal stability of ENL protein in vitro[1].
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Eleven-Nineteen-Leukemia Protein IN-1 | Eleven-Nineteen-Leukemia Protein IN-1 is an inhibitor of ENL YEATS domain with an IC50 value of 14.5 nM. Eleven-Nineteen-Leukemia Protein IN-1 interacts with ENL protein and enhances the thermal stability of ENL protein in vitro. | |||||||||||||||||||||
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