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Results for "

psoralen

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

16

Natural
Products

1

Isotope-Labeled Compounds

1

Click Chemistry

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0053
    Psoralen
    5+ Cited Publications

    Ficusin

    		 Apoptosis HIV Influenza Virus Cancer
    Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al .
    Psoralen
  • HY-30151
    Methoxsalen
    Maximum Cited Publications
    17 Publications Verification

    8-Methoxypsoralen; Xanthotoxin; 8-MOP

    		 Cytochrome P450 Inflammation/Immunology Cancer
    Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
    Methoxsalen
  • HY-10015
    PAP-1
    10+ Cited Publications

    5-(4-Phenoxybutoxy)psoralen

    		 Potassium Channel Inflammation/Immunology
    PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects .
    PAP-1
  • HY-N0235
    Bakuchiol
    2 Publications Verification

    (S)-(+)-Bakuchiol

    		 Carboxylesterase (CES) p38 MAPK Autophagy UGT Infection Metabolic Disease Inflammation/Immunology Cancer
    Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
    Bakuchiol
  • HY-107004A
    Amotosalen hydrochloride
    1 Publications Verification

    S-59

    		 DNA/RNA Synthesis Parasite Inflammation/Immunology
    Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD) .
    Amotosalen hydrochloride
  • HY-137265
    Aminomethyltrioxsalen hydrochloride

    		Flavivirus Infection
    Aminomethyltrioxsalen hydrochloride is a psoralen derivative and nucleic acid intercalator. Aminomethyltrioxsalen hydrochloride can penetrate intact cells and react with nucleic acid secondary structures in vivo without disrupting the tissue structure of natural nucleoproteins. Aminomethyltrioxsalen hydrochloride inactivates viruses by crosslinking nucleic acid pyrimidine residues after exposure to UV-A radiation. Aminomethyltrioxsalen hydrochloride can be used in research related to dengue virus infection .
    Aminomethyltrioxsalen hydrochloride
  • HY-B1157
    Trioxsalen
    3 Publications Verification

    Trisoralen; Trioxysalen; TMP

    		 DNA Alkylator/Crosslinker Inflammation/Immunology
    Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation .
    Trioxsalen
  • HY-150014
    AMT-NHS

    		Others Others
    AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
    AMT-NHS
  • HY-163213
    Psoralen-triethylene glycol azide
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Psoralen-triepthylene glycol azide is a compound used to probe the structure and conformation of RNA in living cells, using matching RNA crosslinking and deep sequencing or comradery methods .
    Psoralen-triethylene glycol azide
  • HY-108583
    Psora-4

    5-(4-Phenylbutoxy)psoralen

    		 Potassium Channel Inflammation/Immunology
    Psora-4 is a potent and selective inhibitor of Kv1.3 (voltage-gated potassium channels) with an EC50 of 3 nM . Psora-4 has immunosuppressive activity and inhibits proliferation of human and rat myelin-specific effector memory T cells in vitro .
    Psora-4
  • HY-N0053R
    Psoralen (Standard)

    Ficusin (Standard)

    		 Reference Standards Apoptosis HIV Influenza Virus Cancer
    Psoralen (Standard) is the analytical standard of Psoralen. This product is intended for research and analytical applications. Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al .
    Psoralen (Standard)
  • HY-N7503
    Psoralenoside

    		Drug Intermediate Bacterial Infection Cancer
    Psoralenoside is an orally active benzofuran glycoside. Psoralenoside is isolated from the fruits of Psoralea corylifolia. As a metabolite precursor, Psoralenoside undergoes deglycosylation by intestinal flora to form Psoralen (HY-N0053). Psoralenoside is applicable to research related to cancer and bacterial infections .
    Psoralenoside
  • HY-N5110
    Marmesinin

    (-)-Marmesinin; Ammijin

    		 Others Neurological Disease
    Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity .
    Marmesinin
  • HY-10015R
    PAP-1 (Standard)

    5-(4-Phenoxybutoxy)psoralen (Standard)

    		 Reference Standards Potassium Channel Inflammation/Immunology
    PAP-1 (Standard) is the analytical standard of PAP-1. This product is intended for research and analytical applications. PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects .
    PAP-1 (Standard)
  • HY-N7504
    Isopsoralenoside

    		Bacterial Infection Metabolic Disease Cancer
    Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
    Isopsoralenoside
  • HY-N0763R
    Angelicin (Standard)

    Isopsoralen (Standard)

    		 Reference Standards Apoptosis Virus Protease Cancer
    Angelicin (Standard) is the analytical standard of Angelicin. This product is intended for research and analytical applications. Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC50: 49.56 μM; inhibits MHV-68, IC50: 5.39 μg/ml (28.95 μM).
    Angelicin (Standard)
  • HY-W777749
    Methoxsalen-13C,d3

    8-Methoxypsoralen-13C,d3; Xanthotoxin-13C,d3; 8-MOP-13C,d3

    		 Isotope-Labeled Compounds Cytochrome P450 Cancer
    Methoxsalen- 13C,d3 (8-Methoxypsoralen- 13C,d3) is the deuterium and 13C-labeled Methoxsalen (HY-30151). Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
    Methoxsalen-13C,d3
  • HY-N0235R
    Bakuchiol (Standard)

    (S)-(+)-Bakuchiol (Standard)

    		 Carboxylesterase (CES) Reference Standards p38 MAPK Autophagy UGT Infection Metabolic Disease Inflammation/Immunology Cancer
    Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
    Bakuchiol (Standard)
  • HY-N9538
    8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen

    		Others Others
    8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam.
    8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen
  • HY-N15589
    8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen

    		Interleukin Related Prostaglandin Receptor TNF Receptor Inflammation/Immunology
    8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen is a compound found in Citrus grandis. 8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen has significant anti-inflammatory activity, which mainly works by inhibiting the secretion of inflammatory factors IL-1β, PGE2 and TNF-α. 8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen can be used in the study of inflammation .
    8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen
  • HY-151116
    HER2-IN-10

    		Apoptosis Cancer
    HER2-IN-10 is a psoralen derivative. HER2-IN-10 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-10 induces apoptosis .
    HER2-IN-10
  • HY-151118
    HER2-IN-11

    		Apoptosis Cancer
    HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis .
    HER2-IN-11
  • HY-30151R
    Methoxsalen (Standard)

    8-Methoxypsoralen (Standard); Xanthotoxin (Standard); 8-MOP (Standard)

    		 Reference Standards Cytochrome P450 Inflammation/Immunology Cancer
    Methoxsalen (Standard) is the analytical standard of Methoxsalen. This product is intended for research and analytical applications. Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
    Methoxsalen (Standard)
  • HY-B1157R
    Trioxsalen (Standard)

    Trisoralen (Standard); Trioxysalen (Standard); TMP (Standard)

    		 Reference Standards DNA Alkylator/Crosslinker Inflammation/Immunology
    Trioxsalen (Standard) is the analytical standard of Trioxsalen. This product is intended for research and analytical applications. Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation .
    Trioxsalen (Standard)
  • HY-107004
    Amotosalen

    S-59 free base

    		 DNA/RNA Synthesis Parasite Inflammation/Immunology
    Amotosalen (S-59 (free base)) is a light-activated, DNA and RNA-crosslinking psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD) .
    Amotosalen
  • HY-182163
    Psoralen C6 phosphoramidite

    		Phosphoramidites
    Psoralen C6 phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    Psoralen C6 phosphoramidite
  • HY-182145
    Psoralen C2 phosphoramidite

    		DNA/RNA Synthesis Phosphoramidites Others
    Psoralen C2 phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    Psoralen C2 phosphoramidite
  • HY-N19667
    8-[2-(3-Methylbutroxy)-3-hydroxy-3-methylbutoxy]psoralen

    		Calcium Channel Neurological Disease Inflammation/Immunology
    8-[2-(3-Methylbutroxy)-3-hydroxy-3-methylbutoxy]psoralen (Compound 12), a furanocoumarin found in the roots of A. archangelica L. archangelica, is an calcium antagonist. 8-[2-(3-Methylbutroxy)-3-hydroxy-3-methylbutoxy]psoralen blocks depolarization-induced calcium uptake in pituitary cells. 8-[2-(3-Methylbutroxy)-3-hydroxy-3-methylbutoxy]psoralen can be used for research on anti-inflammatory and analgesic activities .
    8-[2-(3-Methylbutroxy)-3-hydroxy-3-methylbutoxy]psoralen
  • HY-N9288
    8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen

    		Others Others
    8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Psoralea corylifolia L. .
    8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen
  • HY-N8626
    8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen

    		Others Others
    8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Phebalium tuberculosum ssp. megaphyllum .
    8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen
  • HY-N18751
    Aegle marmelos extract

    		Bacterial Inflammation/Immunology
    Aegle marmelos extract, derived from the Aegle marmelos plant, is rich in various bioactive compounds, such as coumarins (e.g., ligustin, ligustin, ligustin, psoralen, scopolamine, and umbelliferone), flavonoids, phenolic acids, and terpenoids. Aegle marmelos extract possesses anti-inflammatory, antibacterial, antioxidant, antiviral, antifungal, antitumor, and antidiabetic properties.
    Aegle marmelos extract
  • HY-107004AR
    Amotosalen hydrochloride (Standard)

    S-59 (Standard)

    		 Reference Standards DNA/RNA Synthesis Parasite Inflammation/Immunology
    Amotosalen hydrochloride (Standard) (S-59 (Standard)) is the analytical standard of Amotosalen (hydrochloride) (HY-107004A). This product is intended for research and analytical applications. Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinKing psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD) .
    Amotosalen hydrochloride (Standard)

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