62442-61-9
Chemical Structure
Aminomethyltrioxsalen hydrochloride
- CAS No.: 62442-61-9
- Formula:C15H16ClNO3
- Molecular Weight:293.75
IUPAC Name: 3-(aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one hydrochloride
InChIKey: HAWQZPVGCLHOBD-UHFFFAOYSA-N
SMILES: O=C1C=C(C)C2=CC3=C(OC(C)=C3CN)C(C)=C2O1.Cl
Biological Activity: Aminomethyltrioxsalen hydrochloride is a psoralen derivative. Aminomethyltrioxsalen hydrochloride can penetrate intact cells and react with nucleic acid secondary structures in vivo without disrupting the tissue structure of natural nucleoproteins. Aminomethyltrioxsalen hydrochloride inactivates viruses by crosslinking nucleic acid pyrimidine residues after exposure to UV-A radiation. Aminomethyltrioxsalen hydrochloride can be used in research related to dengue virus infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aminomethyltrioxsalen hydrochloride | 99.76% | Aminomethyltrioxsalen hydrochloride is a psoralen derivative. Aminomethyltrioxsalen hydrochloride can penetrate intact cells and react with nucleic acid secondary structures in vivo without disrupting the tissue structure of natural nucleoproteins. Aminomethyltrioxsalen hydrochloride inactivates viruses by crosslinking nucleic acid pyrimidine residues after exposure to UV-A radiation. Aminomethyltrioxsalen hydrochloride can be used in research related to dengue virus infection. | ||||||||||||||||||||
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- [1]. Calvet JP, et al. Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A. 1979;76(2):755-759. [Content Brief]
- [2]. Maves RC, et al. Immunogenicity and protective efficacy of a psoralen-inactivated dengue-1 virus vaccine candidate in Aotus nancymaae monkeys. Vaccine. 2011;29(15):2691-2696. [Content Brief]
Keywords
