2. Apoptosis
  3. Apoptosis
  4. HER2-IN-10

HER2-IN-10 is a psoralen derivative. HER2-IN-10 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-10 induces apoptosis.

For research use only. We do not sell to patients.

HER2-IN-10 Chemical Structure

HER2-IN-10 Chemical Structure

CAS No. : 1059177-03-5

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HER2-IN-10 Related Antibodies

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Description

HER2-IN-10 is a psoralen derivative. HER2-IN-10 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-10 induces apoptosis[1].

In Vitro

HER2-IN-10 (50 µM) has phototoxicity against SK-BR-3 cells with the IC50 of 3.05 µM[1].
HER2-IN-10 (1-50 µM; 48 h) changes the morphology of the SK-BR-3 cells under UVA irradiation and increases the apoptotic index[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HER2-IN-10 Related Antibodies

Apoptosis Analysis[1]

Cell Line: SK-BR-3 cells
Concentration: 1, 2.5, 5, 10, 20 and 50 µM
Incubation Time: 48 hours
Result: Broken down cells into apoptotic bodies at higher concentrations (10, 20, and 50 µM) and cell shrinkage, plasma membrane blebbing at lower concentrations (1, 2.5, and 5 µM).
Molecular Weight

287.27

Formula

C15H13NO5
CAS No.
SMILES

CCC(NC(C1=C(OC=C1)C(OC)=C2O3)=C2C=CC3=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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HER2-IN-10 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HER2-IN-101059177-03-5Apoptosispsoralen derivativeanti-breast cancerlight-activated cytotoxicitySK-BR-3 cellsInhibitorinhibitorinhibit

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