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pulmonary surfactants

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Antibiotic (1) AP-1 (1) Apoptosis (1) Bacterial (2) Biochemical Assay Reagents (1) Elastase (1) Endogenous Metabolite (4) Isotope-Labeled Compounds (3) Liposome (4) NADPH Oxidase (1) NF-κB (1) p38 MAPK (1) Phospholipase (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (3)
Oligonucleotides:	Phospholipids (1)

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Biochemical Assay Reagents

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Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-109506

DPPC 5+ Cited Publications 129Y83	Liposome Endogenous Metabolite	Others
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-P4371

Hel 13-5	Biochemical Assay Reagents	Inflammation/Immunology
Hel 13-5 is a monomeric, lipophilic, basic amphipathic α-helical synthetic peptide composed of 18 amino acid residues. Hel 13-5 is designed as a substitute for proteins in artificial pulmonary surfactants, and it mimics the interaction between the N-terminal fragment of human pulmonary surfactant protein B and lipids. Hel 13-5 can bind to phospholipids for the development of pulmonary surfactant model systems. Hel 13-5 can be used in studies related to respiratory distress syndrome .

HY-130502

5β,6β-Epoxycholestanol Cholesterol 5β,6β-epoxide; 5β,6β-Epoxycholesterol	Apoptosis	Inflammation/Immunology Cancer
5β,6β-epoxycholestanol (Cholesterol 5β,6β-epoxide; 5β,6β-Epoxycholesterol) is an oxysterol. 5β,6β-epoxycholestanol induces cytotoxicity in bronchial epithelial cells. 5β,6β-epoxycholestanol induces lactate dehydrogenase (LDH) release and apoptosis in lymphoma cells undergoing macrophage differentiation . 5β,6β-epoxycholestanol is applicable to research related to atherosclerosis .

HY-109506R

DPPC (Standard) 129Y83 (Standard)	Liposome Reference Standards Endogenous Metabolite	Others
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-109506S9

DPPC-13C2 1 Publications Verification 129Y83-¹³C₂	Isotope-Labeled Compounds Endogenous Metabolite Liposome	Others
DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-136271

MJ33	Phospholipase NADPH Oxidase p38 MAPK Akt NF-κB AP-1 Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology Cancer
MJ-33 is a competitive phospholipase A₂ (PLA₂) inhibitor with an IC₅₀ of 0.3 μM. MJ-33 inhibits the activation of NOX2 by blocking the PLA₂ activity of Prdx6, thereby reducing the production of ROS. MJ-33 effectively inhibits the activity of acidic PLA₂ (pH 4.0), reduces the degradation of pulmonary surfactant phosphatidylcholine (PC), but has no effect on alkaline PLA₂ (pH 8.5). MJ-33 significantly alleviates lung oxidative damage induced by ischemia-reperfusion (I/R). MJ-33 significantly inhibits the invasive, migratory and adhesive abilities of prostate cancer cells by suppressing the MAPK, AKT, NF-κB and AP-1 signaling pathways. MJ-33 can be used to study ROS-related diseases and prostate cancer .

HY-W127442R

Etzadroxil (Standard) Ethyl 2-Ethylbutyrate (Standard)	Bacterial Antibiotic Reference Standards	Others
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-109506S2

(Rac)-DPPC-d6 (Rac)-129Y83-d₆	Isotope-Labeled Compounds	Others
(Rac)-DPPC-d6 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-109506S10

DPPC-13C3 129Y83-¹³C	Isotope-Labeled Compounds Liposome Endogenous Metabolite	Others
DPPC- ¹³C₃ (129Y83- ¹³C) is the ¹³C-labeled DPPC (HY-109506). DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-181647

LasB-IN-3	Bacterial Elastase	Infection
LasB-IN-3 is a protease elastase (LasB) inhibitor of Pseudomonas aeruginosa with an IC₅₀ value of 8.5 nM. LasB-IN-3 shows an IC₅₀ of 58.9 nM for the Met128Val mutant. LasB-IN-3 binds to active sites of wild-type and Met128Val mutant LasB, coordinates zinc ions, forms hydrogen bonds and CH-π interactions, and inhibits LasB proteolytic activity. LasB-IN-3 increases survival rate in LasB-induced acute lung injury mice models. LasB-IN-3 can be used for the research of Pseudomonas aeruginosa infection .

Cat. No.	Product Name	Type

HY-109506

DPPC 5+ Cited Publications 129Y83	Biochemical Assay Reagents
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-130502

5β,6β-Epoxycholestanol Cholesterol 5β,6β-epoxide; 5β,6β-Epoxycholesterol	Biochemical Assay Reagents
5β,6β-epoxycholestanol (Cholesterol 5β,6β-epoxide; 5β,6β-Epoxycholesterol) is an oxysterol. 5β,6β-epoxycholestanol induces cytotoxicity in bronchial epithelial cells. 5β,6β-epoxycholestanol induces lactate dehydrogenase (LDH) release and apoptosis in lymphoma cells undergoing macrophage differentiation . 5β,6β-epoxycholestanol is applicable to research related to atherosclerosis .

HY-109506R

DPPC (Standard) 129Y83 (Standard)	Biochemical Assay Reagents
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

DPPC (Standard)

129Y83 (Standard)

Biochemical Assay Reagents

DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

Cat. No.	Product Name	Target	Research Area

HY-P4371

Hel 13-5	Biochemical Assay Reagents	Inflammation/Immunology
Hel 13-5 is a monomeric, lipophilic, basic amphipathic α-helical synthetic peptide composed of 18 amino acid residues. Hel 13-5 is designed as a substitute for proteins in artificial pulmonary surfactants, and it mimics the interaction between the N-terminal fragment of human pulmonary surfactant protein B and lipids. Hel 13-5 can bind to phospholipids for the development of pulmonary surfactant model systems. Hel 13-5 can be used in studies related to respiratory distress syndrome .

HY-P4371A

Hel 13-5 TFA	Peptides	Others
Hel 13-5 TFA is a monomeric synthetic peptide based on the N-terminal fragment of human SP-B. Hel 13-5 TFA is mainly α-helical and consists of 13 hydrophobic amino acid residues and 5 hydrophilic amino acid residues. Hel 13-5 TFA can be combined with phospholipids for the development of a model system for pulmonary surfactant .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-109506

DPPC 5+ Cited Publications 129Y83	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Lipid Source Classification	Liposome Endogenous Metabolite
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-109506R

DPPC (Standard) 129Y83 (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Liposome Reference Standards Endogenous Metabolite
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

Cat. No.	Product Name	Chemical Structure

HY-109506S9

DPPC-13C2 1 Publications Verification
DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-109506S2

(Rac)-DPPC-d6
(Rac)-DPPC-d6 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-109506S10

DPPC-13C3
DPPC- ¹³C₃ (129Y83- ¹³C) is the ¹³C-labeled DPPC (HY-109506). DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

Cat. No.	Product Name		Classification

HY-109506

DPPC 5+ Cited Publications 129Y83		Phospholipids
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

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pulmonary surfactants

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
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