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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
rOat1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "rOat1" in MCE Product Catalog:
1
Target:
Research Areas:
THIP (Gaboxadol) is a blood-brain barrier-penetrant, orally active selective GABAA receptor agonist. THIP exhibits EC50 values of 33 μM and 130 μM for α4β2δ and α4β1δ receptors, respectively. THIP activates extrasynaptic GABAA receptors to produce tonic inhibition and inhibits GABAergic interneurons to cause disinhibition. THIP is used in research on insomnia, sleep disorders, and addictive behaviors [1] .
Cat. No.: HY-10232S
CAS No.: 2748778-97-2
Synonyms: Gaboxadol-d4
Research Areas:
THIP-d4 (Gaboxadol-d4) is the deuterated-labeled THIP (HY-10232). THIP (Gaboxadol) is a blood-brain barrier-penetrant, orally active selective GABAA receptor agonist. THIP exhibits EC50 values of 33 μM and 130 μM for α4β2δ and α4β1δ receptors, respectively. THIP activates extrasynaptic GABAA receptors to produce tonic inhibition and inhibits GABAergic interneurons to cause disinhibition. THIP is used in research on insomnia, sleep disorders, and addictive behaviors [1] .
Cat. No.: HY-RS13078
Target:
Research Areas:
SLC22A6 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC22A6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-10232R
CAS No.: 64603-91-4
Synonyms: Gaboxadol (Standard)
Target:
Research Areas:
THIP (Gaboxadol) Standard is the analytical standard of THIP (HY-10232). This product is intended for research and analytical applications. THIP (Gaboxadol) is a blood-brain barrier-penetrant, orally active selective GABAA receptor agonist. THIP exhibits EC50 values of 33 μM and 130 μM for α4β2δ and α4β1δ receptors, respectively. THIP activates extrasynaptic GABAA receptors to produce tonic inhibition and inhibits GABAergic interneurons to cause disinhibition. THIP is used in research on insomnia, sleep disorders, and addictive behaviors [1] .
Cat. No.: HY-P704004
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC22A6; Organic Anion Transporter 1; Solute Carrier Family 22 Member 6; PAH Transporter; PAHT; HrOat1; OAT1; HOAT1; rOat1; HPAHT; Solute Carrier Family 22 (Organic Anion Transporter), Member 6; Para-Aminohippurate Transporter; Renal Organic Anion Transpo
Species:
Human
Source:
HEK293
Cat. No.: HY-10232A
CAS No.: 65202-63-3
Synonyms: Gaboxadol (hydrobromid)
Target:
Research Areas:
THIP (Gaboxadol) hydrobromide is a blood-brain barrier-penetrant, orally active selective GABAA receptor agonist. THIP hydrobromide exhibits EC50 values of 33 μM and 130 μM for α4β2δ and α4β1δ receptors, respectively. THIP hydrobromide activates extrasynaptic GABAA receptors to produce tonic inhibition and inhibits GABAergic interneurons to cause disinhibition. THIP hydrobromide is used in research on insomnia, sleep disorders, and addictive behaviors [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
