5 Results for "

receptor-mediated transcytosis

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "receptor-mediated transcytosis" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-172705
Target:  

Liposome nAChR

Research Areas:  

Neurological Disease

DSPE-PEG2000-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG2000-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG2000-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions .
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Cat. No.: HY-P10502
CAS No.: 2378836-93-0
Target:  

LDLR

Research Areas:  

Infection

L57 is a low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 exhibits high affinity for LRP1, with an EC50 of 45 nM. L57 possesses blood-brain barrier (BBB) permeability and plasma stability. L57 can serve as a carrier for central nervous system drug delivery .
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Cat. No.: HY-P10502A
Target:  

LDLR

Research Areas:  

Others

L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 acetate exhibits high affinity to LRP1 with Ki of 45 nM. L57 acetate exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 acetate can be utilized as the carrier for CNS drug delivery .
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Cat. No.: HY-P11771
Research Areas:  

Others

KS-487 is a cyclic peptide targeting LRP1 that binds to cluster IV (CL4) domain of LRP1 and facilitates molecular delivery to brain tissue via receptor-mediated transcytosis (RMT). The EC50 of KS-487 binding to human LRP1 (CL4) is 10.5 nM. Compared with Angiopep-2, KS-487 exhibits enhanced brain selectivity and can be used in studies related to brain-targeted delivery systems .
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Cat. No.: HY-P992048
Synonyms: HIRMab; SHP-631; TAK-531

Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

AGT-182 (HIRMab; SHP-631; TAK-531) is a brain-penetrating anti-human insulin receptor antibody and iduronate-2-sulfatase conjugation. AGT-182 can be used for the research of mucopolysaccharidosis type II (MPS II, Hunter syndrome) .
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