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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
sex hormone-binding globulin
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "sex hormone-binding globulin" in MCE Product Catalog:
Cat. No.: HY-W727992
CAS No.: 34730-78-4
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Equilenin is a B-ring unsaturated estrogen discovered in pregnant mare urine and is one of the major components of Premarin, a drug commonly used for estrogen replacement therapy. Equilenin binds to estrogen receptors in the body and exerts effects similar to endogenous estrogens. Equilenin weakly binds to and activates the aryl hydrocarbon receptor (AhR) to induce CYP1A1 expression. Equilenin exhibits high affinity for sex hormone-binding globulin (SHBG/SBP) and is metabolized by CYP1A1/1B1 to 4-hydroxy and 17β-dihydro derivatives. Equilenin is used in breast cancer-related research .
Cat. No.: HY-118124
CAS No.: 24381-12-2
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2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research .
Cat. No.: HY-N13215
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Tongkat Ali Extract is the extract of Tongkat Ali, a testosterone modulator. Tongkat Ali Extract activates CYP17 enzyme to enhance conversion of pregnenolone and progesterone to dehydroepiandrosterone, androstenedione, and testosterone. Tongkat Ali Extract demonstrates antimalarial, antimicrobial, anticancer, and antidiabetic activity. Tongkat Ali Extract can be used for the research of diabetic and male infertility .
Cat. No.: HY-116865S
CAS No.: 56588-54-6
Equilenin-4,16,16-d3 is the d3-labeled Equilenin (HY-116865). Equilenin is a B-ring unsaturated estrogen discovered in pregnant mare urine and is one of the major components of Premarin, a drug commonly used for estrogen replacement therapy. Equilenin binds to estrogen receptors in the body and exerts effects similar to endogenous estrogens. Equilenin weakly binds to and activates the aryl hydrocarbon receptor (AhR) to induce CYP1A1 expression. Equilenin exhibits high affinity for sex hormone-binding globulin (SHBG/SBP) and is metabolized by CYP1A1/1B1 to 4-hydroxy and 17β-dihydro derivatives. Equilenin is used in breast cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
