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smaller liposomes

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3

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136304
    NHS-PEG1-SS-PEG1-NHS

    		PROTAC Linkers Cardiovascular Disease Metabolic Disease Cancer
    NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .
    NHS-PEG1-SS-PEG1-NHS
  • HY-W416291
    Polyadenylic acid potassium

    Poly(A)

    		 Biochemical Assay Reagents Cancer
    Polyadenylic acid potassium, also known as Poly(A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly(A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly(A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly(A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents.
    Polyadenylic acid potassium
  • HY-142989
    1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine

    		Liposome HIV HCV HBV Infection Cancer
    1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .
    1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine
  • HY-159194
    DSPE-PEG2000-Cy5.5

    		Liposome Cancer
    DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer .
    DSPE-PEG2000-Cy5.5
  • HY-126967A
    1-Palmitoyl-sn-glycerol 3-phosphate

    1-P-GPA

    		 Liposome Cardiovascular Disease
    1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is a phospholipid and lipid membrane precursor. 1-Palmitoyl-sn-glycerol 3-phosphate integrates into POPC liposomes, causing significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate induces platelet aggregation, but its activity is 30-fold lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate .
    1-Palmitoyl-sn-glycerol 3-phosphate
  • HY-112005GL
    DOPE (GMP Like)

    Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)

    		 Liposome Endogenous Metabolite Inflammation/Immunology
    DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
    DOPE (GMP Like)
  • HY-112764GL
    DMG-PEG 2000 (GMP Like)

    		Liposome Metabolic Disease
    DMG-PEG 2000 (GMP Like) is DMG-PEG 2000 (HY-112764) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
    DMG-PEG 2000 (GMP Like)
  • HY-W040193GL
    DSPC (GMP Like)

    1,2-Distearoyl-sn-glycero-3-PC (GMP Like); 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (GMP Like)

    		 Liposome Others
    DSPC (GMP Like) (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is DSPC (HY-W040193) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
    DSPC (GMP Like)
  • HY-182833A
    DPPE-PEG2000-NHS

    		Biochemical Assay Reagents Others
    DPPE-PEG2000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DPPE-PEG2000-NHS
  • HY-182833D
    DPPE-PEG10000-NHS

    		Biochemical Assay Reagents Others
    DPPE-PEG10000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DPPE-PEG10000-NHS
  • HY-182833B
    DPPE-PEG3400-NHS

    		Biochemical Assay Reagents Others
    DPPE-PEG3400-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DPPE-PEG3400-NHS
  • HY-183104D
    DSG-PEG10000-NHS

    		Biochemical Assay Reagents Others
    DSG-PEG10000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DSG-PEG10000-NHS
  • HY-183104
    DSG-PEG1000-NHS

    		Biochemical Assay Reagents Others
    DSG-PEG1000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DSG-PEG1000-NHS
  • HY-183016
    DMPE-PEG1000-NHS

    		Biochemical Assay Reagents Others
    DMPE-PEG1000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DMPE-PEG1000-NHS
  • HY-183104B
    DSG-PEG3400-NHS

    		Biochemical Assay Reagents Others
    DSG-PEG3400-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DSG-PEG3400-NHS
  • HY-183104A
    DSG-PEG2000-NHS

    		Biochemical Assay Reagents Others
    DSG-PEG2000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DSG-PEG2000-NHS
  • HY-183016C
    DMPE-PEG5000-NHS

    		Biochemical Assay Reagents Others
    DMPE-PEG5000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DMPE-PEG5000-NHS
  • HY-183016B
    DMPE-PEG3400-NHS

    		Biochemical Assay Reagents Others
    DMPE-PEG3400-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DMPE-PEG3400-NHS
  • HY-182833
    DPPE-PEG1000-NHS

    		Biochemical Assay Reagents Others
    DPPE-PEG1000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DPPE-PEG1000-NHS
  • HY-183104C
    DSG-PEG5000-NHS

    		Biochemical Assay Reagents Others
    DSG-PEG5000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DSG-PEG5000-NHS
  • HY-182833C
    DPPE-PEG5000-NHS

    		Biochemical Assay Reagents Others
    DPPE-PEG5000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DPPE-PEG5000-NHS
  • HY-183016A
    DMPE-PEG2000-NHS

    		Biochemical Assay Reagents Others
    DMPE-PEG2000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DMPE-PEG2000-NHS
  • HY-183016D
    DMPE-PEG10000-NHS

    		Biochemical Assay Reagents Others
    DMPE-PEG10000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
    DMPE-PEG10000-NHS

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