7220-34-0
7220-34-0
Chemical Structure
1-Palmitoyl-sn-glycerol 3-phosphate
Synonym(s): 1-P-GPA
- CAS No.: 7220-34-0
- Formula:C19H39O7P
- Molecular Weight:410.48
IUPAC Name: (R)-2-hydroxy-3-(phosphonooxy)propyl palmitate
InChIKey: YNDYKPRNFWPPFU-GOSISDBHSA-N
SMILES: O=P(O)(O)OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O
Biological Activity: 1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is a phospholipid and lipid membrane precursor. 1-Palmitoyl-sn-glycerol 3-phosphate integrates into POPC liposomes, causing significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate induces platelet aggregation, but its activity is 30-fold lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate[1][2].
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1-Palmitoyl-sn-glycerol 3-phosphate | 1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is a phospholipid and lipid membrane precursor. 1-Palmitoyl-sn-glycerol 3-phosphate integrates into POPC liposomes, causing significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate induces platelet aggregation, but its activity is 30-fold lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate. | |||||||||||||||||||||
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1-Palmitoyl-sn-glycerol 3-phosphate-d9 | 1-Palmitoyl-sn-glycerol 3-phosphate-d9 is the deuterium labeled 1-Palmitoyl-sn-glycerol 3-phosphate (1-Palmitoyl LPA). 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid at the sn-1 position. | |||||||||||||||||||||
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References
- [1]. Wick R, et al. Enzyme-containing liposomes can endogenously produce membrane-constituting lipids. Chem Biol. 1996;3(4):277-285. [Content Brief]
- [2]. Simon MF, et al. Human platelet aggregation induced by 1-alkyl-lysophosphatidic acid and its analogs: a new group of phospholipid mediators? Biochem Biophys Res Commun. 1982 Oct 29;108(4):1743-50. [Content Brief]
