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tetrazine ligation

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134599
    (2E)-TCO-PNB ester

    		Biochemical Assay Reagents Cancer
    (2E)-TCO-PNB ester is an active reaction substrate with the properties of trans-cyclooctene derivatives. The core chemical property of (2E)-TCO-PNB ester is its ability to undergo efficient inverse electron-demand Diels-Alder (IEDDA) cycloaddition with tetrazine groups. (2E)-TCO-PNB ester can be used in ligation reactions to verify the integrity of tetrazine groups, and also serves as a key synthetic raw material for the preparation of the prodrug TCO-DOX. (2E)-TCO-PNB ester is applied in research related to drug synthesis and bioorthogonal chemistry .
    (2E)-TCO-PNB ester
  • HY-164785
    TCO-PEG5-C2-Mal

    		Drug Intermediate Others
    TCO-PEG5-maleimide is a PEG linker with TCO and maleimide groups, specifically enabling tetrazine click chemistry and thiol conjugation for bioconjugation, probe design, and drug delivery.
    TCO-PEG5-C2-Mal
  • HY-157006A
    TCO-PEG3-NH2

    		Biochemical Assay Reagents Others
    TCO-PEG3-NH2 is a click chemistry reagent that contains a TCO group and undergoes the inverse electron-demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules .
    TCO-PEG3-NH2

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