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Results for "

tetrazine moiety

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Biochemical Assay Reagents (7) Fluorescent Dye (6)
By Research Areas:	Cancer (1)
Click Chemistry:	TCO (1) Labeling and Fluorescence Imaging (3) DBCO (1) Tetrazine (5)

Inhibitors & Agonists

Fluorescent Dyes

Click Chemistry

Targets Recommended: Ligands for Target Protein for PROTAC Ligands for E3 Ligase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134599

(2E)-TCO-PNB ester	Biochemical Assay Reagents	Cancer
(2E)-TCO-PNB ester is an active reaction substrate with the properties of trans-cyclooctene derivatives. The core chemical property of (2E)-TCO-PNB ester is its ability to undergo efficient inverse electron-demand Diels-Alder (IEDDA) cycloaddition with tetrazine groups. (2E)-TCO-PNB ester can be used in ligation reactions to verify the integrity of tetrazine groups, and also serves as a key synthetic raw material for the preparation of the prodrug TCO-DOX. (2E)-TCO-PNB ester is applied in research related to drug synthesis and bioorthogonal chemistry .

HY-D1554

Cyanine5 tetrazine	Fluorescent Dye	Others
Cyanine5 tetrazine, a fluorophore, is a molecule that contains a cyano5 fluorophore and a tetrazine moiety .

HY-D2489

Cy5-tetrazine	Fluorescent Dye	Others
Cy5-tetrazine is a fluorescent dye. Cy5-tetrazine is a CY5 (HY-D0821) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .

HY-D1071

DBCO-PEG12-TCO	Fluorescent Dye	Others
DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-D1557

Cyanine5.5 tetrazine	Fluorescent Dye	Others
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-160258

GDP-Fucose-Tz GDP-Fucose-Am-Tz	Biochemical Assay Reagents	Others
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a non-natural GDP-fucose analog bearing a Tetrazine group. As a precursor, GDP-Fucose-Tz enables the synthesis of GDP-fucose-ssDNA probes via inverse electron demand Diels-Alder reaction. GDP-Fucose-Tz participates in chemoenzymatic reactions to prepare GDP-fucose-Herceptin derivatives through conjugation with TCO-Herceptin .

HY-151769

TCO-PEG2-Sulfo-NHS ester-EDC Urea	ADC Linker	Others
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-157006A

TCO-PEG3-NH2	Biochemical Assay Reagents	Others
TCO-PEG3-NH2 is a click chemistry reagent that contains a TCO group and undergoes the inverse electron-demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules .

HY-151686

Bz-(Me)Tz-NHS	Biochemical Assay Reagents	Others
Bz-(Me)Tz-NHS is a methyltetrazine carboxylic acid NHS ester that enables conjugation of the tetrazine moiety to the 5' end of oligonucleotides via amide coupling reaction, and it is used in oligonucleotide template-mediated fluorescent bioorthogonal cycloaddition reactions. Bz-(Me) Tz-NHS is applicable to click chemistry-related studies .

HY-W800817

TCO-PEG4-maleimide	Biochemical Assay Reagents	Others
TCO-PEG4-maleimide is a click chemistry building block containing a TCO moiety and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond. TCO moiety is very reactive with tetrazine (3rd generation click chemistry).

HY-D1598

Sulfo-CY3 tetrazine potassium	Fluorescent Dye	Others
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D2040

5-ROX tetrazine	Fluorescent Dye	Others
ROX tetrazine is a derivative of ROX (Rhodamine X, Rhodamine 101) dye, a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This compound contains tetrazine moiety that reacts with trans-cycloalkenes and other strained olefins in inverse electron demand Diels-Alder reaction (IEDDA). The reaction is very quick and specific.

HY-W190914

Tco-PEG2-Tco	Biochemical Assay Reagents	Others
TCO-PEG2-TCO is a homebifunctional reagent containing TCO moiety at both ends of the molecule. TCO group specifically and efficiently reacts with tetrazine. The hydrophilic PEG linker increases the solubility of compounds in aqueous media.

HY-183964

DSPE-PEG2000-tetrazine	Biochemical Assay Reagents	Others
DSPE-PEG2000-tetrazine is a synthetic phospholipid modified with PEG2000 and tetrazine moieties. DSPE-PEG2000-tetrazine gains improved steric stability via PEGylation. DSPE-PEG2000-tetrazine enables bioorthogonal click chemistry through its tetrazine segment, which selectively reacts with trans-cyclooctene (TCO) under complex biological environments. DSPE-PEG2000-tetrazine can be applied for researches related to click chemistry .

Cat. No.	Product Name	Type

HY-D2489

Cy5-tetrazine	Fluorescent Dyes
Cy5-tetrazine is a fluorescent dye. Cy5-tetrazine is a CY5 (HY-D0821) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .

HY-D1071

DBCO-PEG12-TCO	Fluorescent Dyes
DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

DBCO-PEG12-TCO

Fluorescent Dyes

DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-D1557

Cyanine5.5 tetrazine	Fluorescent Dyes
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Cyanine5.5 tetrazine

Fluorescent Dyes

Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D1598

Sulfo-CY3 tetrazine potassium	Fluorescent Dyes
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Sulfo-CY3 tetrazine potassium

Fluorescent Dyes

Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D2040

5-ROX tetrazine	Fluorescent Dyes
ROX tetrazine is a derivative of ROX (Rhodamine X, Rhodamine 101) dye, a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This compound contains tetrazine moiety that reacts with trans-cycloalkenes and other strained olefins in inverse electron demand Diels-Alder reaction (IEDDA). The reaction is very quick and specific.

Cat. No.	Product Name		Classification

HY-D1071

DBCO-PEG12-TCO		DBCO
DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-D1557

Cyanine5.5 tetrazine		Labeling and Fluorescence Imaging Tetrazine
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-160258

GDP-Fucose-Tz GDP-Fucose-Am-Tz		Tetrazine
GDP-Fucose-Tz (GDP-Fucose-Am-Tz) is a non-natural GDP-fucose analog bearing a Tetrazine group. As a precursor, GDP-Fucose-Tz enables the synthesis of GDP-fucose-ssDNA probes via inverse electron demand Diels-Alder reaction. GDP-Fucose-Tz participates in chemoenzymatic reactions to prepare GDP-fucose-Herceptin derivatives through conjugation with TCO-Herceptin .

HY-151769

TCO-PEG2-Sulfo-NHS ester-EDC Urea		TCO Labeling and Fluorescence Imaging
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-151686

Bz-(Me)Tz-NHS		Tetrazine
Bz-(Me)Tz-NHS is a methyltetrazine carboxylic acid NHS ester that enables conjugation of the tetrazine moiety to the 5' end of oligonucleotides via amide coupling reaction, and it is used in oligonucleotide template-mediated fluorescent bioorthogonal cycloaddition reactions. Bz-(Me) Tz-NHS is applicable to click chemistry-related studies .

HY-D1598

Sulfo-CY3 tetrazine potassium		Tetrazine Labeling and Fluorescence Imaging
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D2040

5-ROX tetrazine		Tetrazine
ROX tetrazine is a derivative of ROX (Rhodamine X, Rhodamine 101) dye, a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This compound contains tetrazine moiety that reacts with trans-cycloalkenes and other strained olefins in inverse electron demand Diels-Alder reaction (IEDDA). The reaction is very quick and specific.

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