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Cat. No.: HY-183964

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DSPE-PEG2000-tetrazine

DSPE-PEG2000-tetrazine is a synthetic phospholipid modified with PEG2000 and tetrazine moieties. DSPE-PEG2000-tetrazine gains improved steric stability via PEGylation. DSPE-PEG2000-tetrazine enables bioorthogonal click chemistry through its tetrazine segment, which selectively reacts with trans-cyclooctene (TCO) under complex biological environments. DSPE-PEG2000-tetrazine can be applied for researches related to click chemistry.

For research use only. We do not sell to patients.

CAS No.: 3101670-39-4
Molecular Weight:2000 (Average)

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DSPE-PEG2000-tetrazine Chemical Structure

CAS No.: 3101670-39-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

In Vitro

DSPE-PEG2000-tetrazine enables successful conjugation of Rhodamine-CRM₁₉₇-TCO to PLGA/lipid hybrid nanoparticles via TCO-tetrazine click chemistry^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3101670-39-4
Molecular Weight 2000 (Average)
SMILES

CCCCCCCCCCCCCCCCCC(O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(OCCOCCNC(CC1=CC=C(C=C1)C2=NN=CN=N2)=O)=O)(O)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hu H, et al. Conjugation of Multiple Proteins Onto the Surface of PLGA/Lipid Hybrid Nanoparticles. J Biomed Mater Res A. 2025;113(1):e37807. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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