966 Results for "

transport

" in MedChemExpress (MCE) Product Catalog:
Products (966)

966 Results for "transport" in MCE Product Catalog:

  • Targets Recommended:
199
199 Publications Verification
Cat. No.: HY-B1756
CAS No.: 83-79-4
Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.
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170
170 Cited Publications
Cat. No.: HY-16592
CAS No.: 20350-15-6
Synonyms: BFA; Cyanein; Decumbin
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus . Brefeldin A is also an autophagy and mitophagy inhibitor . Brefeldin A inhibits HSV-1 and has anti-cancer activity .
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119
119 Cited Publications
Cat. No.: HY-N6782
CAS No.: 1404-19-9
Oligomycin, an antifungal antibiotic, is an inhibitor of H +-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells .
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48
48 Cited Publications
Cat. No.: HY-10465
CAS No.: 1009119-65-6
Purity:  99.68%
Synonyms: BMS-790052 dihydrochloride; EBP 883 dihydrochloride
Target:  

HCV

Research Areas:  

Infection

Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
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48
48 Cited Publications
Cat. No.: HY-10466
CAS No.: 1009119-64-5
Purity:  98.68%
Synonyms: BMS-790052; EBP 883
Target:  

HCV

Research Areas:  

Infection

Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively .
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45
45 Cited Publications
Cat. No.: HY-112847A
Purity:  ≥98.0%
Synonyms: Sulfo-N-succinimidyl oleate sodium
Target:  

Mitophagy

Research Areas:  

Inflammation/Immunology

Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
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44
44 Cited Publications
Cat. No.: HY-D0843
CAS No.: 128-53-0
Synonyms: NEM
Category:  

Microorganisms

N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .
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29
29 Cited Publications
Cat. No.: HY-107433
CAS No.: 3039-71-2
Purity:  99.77%
Research Areas:  

Infection Neurological Disease

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus .
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28
28 Cited Publications
Cat. No.: HY-101086
CAS No.: 2260-50-6
Purity:  98.59%
Synonyms: ACh iodide
Acetylcholine iodide is a muscarinic receptor modulator. Acetylcholine iodide specifically binds to muscarinic receptors, inhibits sodium absorption, and induces chloride secretion. Acetylcholine iodide changes intestinal ion transport, enhances intestinal secretory function, induces or maintains mammary gland development and lactation. Acetylcholine iodide can be used for intestinal ion transport regulation and mammary gland physiological function research .
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27
27 Cited Publications
Cat. No.: HY-W011777
CAS No.: 886-86-2
Synonyms: MS-222
Research Areas:  

Neurological Disease

Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures .
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25
25 Cited Publications
Cat. No.: HY-N0455
CAS No.: 74-79-3
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .
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25
25 Cited Publications
Cat. No.: HY-N0455A
CAS No.: 1119-34-2
Synonyms: (S)-(+)-Arginine hydrochloride
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .
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25
25 Cited Publications
Cat. No.: HY-108717
CAS No.: 39450-01-6
Synonyms: Protease K
Target:  

Ser/Thr Protease

Research Areas:  

Others

Proteinase K (Protease K) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K can be use for promoting methods of viral nucleic acid extraction, and detection .
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24
24 Cited Publications
Cat. No.: HY-N7131
CAS No.: 38215-36-0
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .
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22
22 Cited Publications
Cat. No.: HY-B0399
CAS No.: 541-15-1
Synonyms: (R)-Carnitine; Levocarnitine
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .
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22
22 Cited Publications
Cat. No.: HY-B2246
CAS No.: 6645-46-1
Synonyms: (R)-Carnitine hydrochloride; Levocarnitine hydrochloride
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .
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22
22 Cited Publications
Cat. No.: HY-W105518
CAS No.: 36687-82-8
L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism [3] .
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18
18 Cited Publications
Cat. No.: HY-N6684
CAS No.: 51481-10-8
Synonyms: Vomitoxin
Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors .
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16
16 Cited Publications
Cat. No.: HY-101091
CAS No.: 662163-81-7
Purity:  99.71%
Target:  

Apoptosis

Research Areas:  

Cancer

Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
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16
16 Cited Publications
Cat. No.: HY-N0111
CAS No.: 303-98-0
Synonyms: CoQ10; Ubiquinone-10; Ubidecarenone
Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
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