18 Results for "

tslpr

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "tslpr" in MCE Product Catalog:

Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-RS03187
Research Areas:  

Others

CRLF2 Human Pre-designed siRNA Set A contains three designed siRNAs for CRLF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25299
Research Areas:  

Others

Crlf2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Crlf2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-206870
CAS No.: 3104965-33-2
Research Areas:  

Inflammation/Immunology

BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis .
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Cat. No.: HY-P84809A
Synonyms: CRL2; tslpr; CRLF2Y

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84809
Synonyms: CRL2; tslpr; CRLF2Y

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P71389
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; tslpr; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705242
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; tslpr; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704719
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 Receptor; Interleukin 7 Receptor; IL-7 Receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 Receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 Receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70794
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; tslpr; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P2RY8; TSLP Receptor; ILXR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700842
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; tslpr; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P70823
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; tslpr; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P70989
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; tslpr; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-RS18809
Research Areas:  

Others

Crlf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Crlf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-207120
CAS No.: 512837-95-5
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TSLP-IN-1 is a potent thymic stromal lymphopoietin (TSLP) inhibitor. TSLP-IN-1 disrupts TSLP-TSLPR protein-protein interaction, and downregulates IL-4 and IL-13. TSLP-IN-1 can be used for the research of inflammation diseases, such as skin disease, asthma, and allergies .
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Cat. No.: HY-P992447

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a KD value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of TSLP-TSLPR-IL-7Rα. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma .
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Cat. No.: HY-P703696
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 Receptor; Interleukin 7 Receptor; IL-7 Receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 Receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 Receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704720
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 Receptor; Interleukin 7 Receptor; IL-7 Receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 Receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 Receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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