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Results for "

van der Waals forces

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W020780
    mPEG5000-Mal

    mPEG5000-Maleimide

    		 Biochemical Assay Reagents Cancer
    mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .
    mPEG5000-Mal
  • HY-W009708
    Bis(2-methyl-3-furyl)disulfide

    		Mucin Others
    Bis (2-methyl-3-furyl) disulfide is a meat-characteristic aroma compound that binds to oral mucins. Bis (2-methyl-3-furyl) disulfide interacts with oral mucins via hydrogen bonding, hydrophobic interactions and van der Waals forces to form stable spontaneous 1:1 complexes, and the interaction strength varies with pH. Bis (2-methyl-3-furyl) disulfide contributes to the production of unique meat aroma and flavor, and its binding to oral mucins alters aroma perception .
    Bis(2-methyl-3-furyl)disulfide
  • HY-W009708R
    Bis(2-methyl-3-furyl)disulfide (Standard)

    		Reference Standards Mucin Others
    Bis(2-methyl-3-furyl)disulfide (Standard) is the analytical standard of Bis(2-methyl-3-furyl)disulfide. This product is used for research and analytical applications. Bis(2-methyl-3-furyl)disulfide is a meat flavor characteristic aroma compound that can bind to oral mucin. Bis(2-methyl-3-furyl)disulfide can interact with oral mucin through hydrogen bonds, hydrophobic interactions, and van der Waals forces to form a stable spontaneous 1:1 complex, and the interaction intensity varies with pH. Bis(2-methyl-3-furyl)disulfide helps to produce unique meat aroma and flavor, and its binding to oral mucin will change the perception of aroma.
    Bis(2-methyl-3-furyl)disulfide (Standard)
  • HY-128299
    ALDH3A1-IN-4

    		Aldehyde Dehydrogenase (ALDH) Neurological Disease Cancer
    ALDH3A1-IN-4 is a selective ALDH3A1 inhibitor with an IC50 of 0.2 μM. ALDH3A1-IN-4 binds to the aldehyde-binding pocket of ALDH3A1 via hydrophobic interactions and van der Waals forces. ALDH3A1-IN-4 acts as a chemosensitizer that sensitizes ALDH3A1-expressing cancer cells to the antiproliferative effect of mafosfamide, but does not produce a sensitizing effect on non-cancer cells that do not express ALDH3A1. ALDH3A1-IN-4 is applicable to research related to lung adenocarcinoma and glioblastoma .
    ALDH3A1-IN-4

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