Search Result

Results for "

vivo imaging

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (3) Apoptosis (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (4) Bombesin Receptor (1) Calcium Channel (2) Chloride Channel (1) COX (1) Cytochrome P450 (1) Dopamine Receptor (1) Ephrin Receptor (1) FAAH (1) FAP (1) Fluorescent Dye (121) GABA Receptor (1) GLUT (1) Glycosidase (2) HDAC (2) HIF/HIF Prolyl-Hydroxylase (1) HSP (1) iGluR (2) Integrin (1) Isotope-Labeled Compounds (2) Liposome (4) MAGL (1) Melanocortin Receptor (2) Mitochondrial Metabolism (3) Mitophagy (1) MOFs (1) Monoamine Oxidase (2) Opioid Receptor (1) Orexin Receptor (OX Receptor) (1) Phosphodiesterase (PDE) (1) PSMA (2) Radionuclide-Drug Conjugates (RDCs) (2) Reactive Oxygen Species (ROS) (4) Reference Standards (1) Sigma Receptor (1) Tau Protein (2) TROP2 (1) TSPO (2)
By Research Areas:	Cancer (34) Cardiovascular Disease (3) Infection (1) Inflammation/Immunology (8) Metabolic Disease (4) Neurological Disease (24)
Click Chemistry:	Labeling and Fluorescence Imaging (1) DBCO (1) Tetrazine (2)
Oligonucleotides:	Fluorescent Lipids (3) Pegylated Lipids (3) mRNA (1) Cholesterol (1)

163

Inhibitors & Agonists

106

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1041

ICG NHS ester ICG-OSu	Fluorescent Dye	Cancer
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .

HY-111653

CycLuc1 2 Publications Verification	Reactive Oxygen Species (ROS)	Others
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .

HY-133852

FD-1080 1 Publications Verification	Fluorescent Dye MOFs	Others
FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .

HY-133852A

FD-1080 free acid 1 Publications Verification	Fluorescent Dye	Others
FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging .

HY-D1464

CH1055 1 Publications Verification	Fluorescent Dye	Cancer
CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .

HY-D1449

IR-1061 1 Publications Verification	Fluorescent Dye	Others
IR-1061 is a near infrared fluorescent organic dye for in vivo bimodal imaging .

HY-D1873

800CW acid	Fluorescent Dye	Others
800CW acid is an orally active near-infrared (NIR) dye (excitation/emission 774/789 nm). 800CW acid can be used for intestinal permeability testing. 800CW acid can be used for in vivo imaging studies .

HY-47176

QTZ	Fluorescent Dye	Others
QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core .

HY-D1719

Cypate 1 Publications Verification	Fluorescent Dye	Others
Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .

HY-135368

8pyDTZ 3 Publications Verification	Fluorescent Dye	Others
8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging .

HY-122607

DPA-714	Mitochondrial Metabolism TSPO	Inflammation/Immunology Cancer
DPA-714 is a high affinity translocator protein (TSPO) ligand (K_i=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. ^18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model .

HY-D1707

FDGlcU	Fluorescent Dye	Others
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .

HY-101183

THK5351	Tau Protein	Neurological Disease
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.

HY-B0594S

Iohexol-d5	Isotope-Labeled Compounds Autophagy Mitophagy	Cancer
Iohexol-d₅ is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography?(cisternography, ventriculography) and MicroCT imaging in vivo .

HY-P11057

FGGH	Fluorescent Dye	Others
FGGH is a water-soluble peptide-based probe. FGGH performs the sequential detection of Cu ²⁺ and S ^2- by fluorescence and colorimetry with high sensitivity (LOD: 1.42 and 22.2 nM for Cu ²⁺ and S ^2-, respectively) (Ex=488 nm, Em=525 nm), and images both two ions in living cells and zebrafish models with low cytotoxicity. FGGH can be used for in vivo imaging and environmental pollution monitoring research .

HY-D2062

ATTO 740 NHS ester	Fluorescent Dye Integrin	Cancer
ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .

HY-D2640

Cy5 HA (MW 5000)	Fluorescent Dye	Others
Cy5 HA (MW 5000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-160092A

Martinostat hydrochloride	HDAC	Neurological Disease
Martinostat hydrochloride is a HDAC inhibitor and can be labeled with radionuclides for quantitative imaging of HDACs in vivo in the central nervous system and major peripheral organs .

HY-DY1072

ICG NHS ester (solution) ICG-OSu (solution)	Fluorescent Dye	Cancer
ICG NHS ester (ICG-OSu) (solution) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes . Solvent and concentration: DMSO: 10 mM

HY-D1557

Cyanine5.5 tetrazine	Fluorescent Dye	Others
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D1464A

CH1055 triethylamine 1 Publications Verification	Fluorescent Dye	Cancer
CH1055 triethylamine is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 triethylamine can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .

HY-D2647

Cy5 HA (MW 500000)	Fluorescent Dye	Others
Cy5 HA (MW 500000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-155002

hCYP3A4 Fluorogenic substrate 1	Cytochrome P450	Metabolic Disease
hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an K_m value of 0.36 μM. hCYP3A4 Fluorogenic substrate 1 can be used for cell and in vivo imaging .

HY-100723

THK-523	Amyloid-β	Neurological Disease
THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. ¹⁸F-THK523 is a potent tau imaging radiotracer. ¹⁸F-THK523 is a potent in vivo tau imaging ligand for Alzheimer's disease .

HY-D2645

Cy5 HA (MW 100000)	Fluorescent Dye	Others
Cy5 HA (MW 100000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-D2638

Cy5 HA (MW 3000)	Fluorescent Dye	Others
Cy5 HA (MW 3000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-147507

SBP-1	Fluorescent Dye	Others
SBP-1 is a sulfite bioluminescent probe (SBP). SBP-1 exhibits the excellent responsivity, selectivity and sensitivity towards sulfite. The recognition of SBP-1 towards sulfite is based on the mechanism of a sulfite-mediated intramolecular cleavage reaction. SBP-1 can be used for detection of exogenous and endogenous sulfite in living animal. SBP-1 also possesses a capability for quantitatively detecting sulfite within a certain concentration range in solution .

HY-D2642

Cy5 HA (MW 10000)	Fluorescent Dye	Others
Cy5 HA (MW 10000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-D2624

Cy3 HA (MW 10000)	Fluorescent Dye	Others
Cy3 HA (MW 10000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).

HY-D2625

Cy3 HA (MW 50000)	Fluorescent Dye	Others
Cy3 HA (MW 50000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).

HY-D2646

Cy5 HA (MW 200000)	Fluorescent Dye	Others
Cy5 HA (MW 200000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-D2676

Cy7 HA (MW 50000)	Fluorescent Dye	Others
Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).

HY-D2653

Cy5 HA biotin 3000	Fluorescent Dye	Others
Cy5 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).

HY-149298

PSMA-IN-2	PSMA	Cancer
PSMA-IN-2 is an inhibitor of PSMA with a K_i value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λ_EM = 1088 nm, λ_ex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice .

HY-141646

MIT-PZR	Fluorescent Dye	Others
MIT-PZR is a mitochondria-targeted,? low cytotoxicity fluorescent probe that can be used in live cells and in vivo imaging. Ex / Em = 485 / 705 nm

HY-160092

Martinostat	HDAC	Neurological Disease
Martinostat is a HDAC inhibitor and can be labeled with radionuclides for quantitative imaging of HDACs in vivo in the central nervous system and major peripheral organs .

HY-D2663

Cy5.5 HA (MW 500000)	Fluorescent Dye	Others
Cy5.5 HA (MW 500000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).

HY-D2671

Cy5.5 HA biotin 10000	Fluorescent Dye	Others
Cy5.5 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).

HY-D1391

PbS/CdS QDs PbS/CdSe QD	Fluorescent Dye	Others
PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .

HY-145128

GR103545 fumarate	Opioid Receptor	Neurological Disease
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). ¹¹GR103545 is a radiotracer for imaging κ-OR in vivo ^[1]

HY-D2217

Cy7 tetrazine	Fluorescent Dye	Others
Cy7 tetrazine is a near infrared dye that can be used for in vivo imaging .

HY-160276

DOPE-PEG5000-Fluor 555	Liposome	Others
DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.

HY-168571

BTF	Orexin Receptor (OX Receptor)	Neurological Disease
BTF shows a selective binding affinity for OX1R with the K_i values of 2.33 nM and 62.8 nM of OX1R and OX2R, respectively .

HY-D2621

Cy3 HA (MW 5000)	Fluorescent Dye	Others
Cy3 HA (MW 5000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).

HY-D2641

Cy5 HA (MW 7000)	Fluorescent Dye	Others
Cy5 HA (MW 7000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-D2677

Cy7 HA (MW 100000)	Fluorescent Dye	Others
Cy7 HA (MW 100000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).

HY-D2675

Cy7 HA (MW 10000)	Fluorescent Dye	Others
Cy7 HA (MW 10000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).

HY-D2643

Cy5 HA (MW 50000)	Fluorescent Dye	Others
Cy5 HA (MW 50000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).

HY-D2674

Cy7 HA (MW 7000)	Fluorescent Dye	Others
Cy7 HA (MW 7000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).

HY-D2622

Cy3 HA (MW 3000)	Fluorescent Dye	Others
Cy3 HA (MW 3000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).

Cat. No.	Product Name	Type

HY-W440911

DSPE-PEG2000-Cy5

Biochemical Assay Reagents

DSPE-PEG2000-Cy5 is a Cy5 (HY-D0821) fluorophore-labeled conjugate of distearoylphosphatidylethanolamine and polyethylene glycol, as well as a liposome component. The Cy5 fluorophore is commonly used for labeling proteins and nucleic acids in imaging, flow cytometry and genomic applications. DSPE-PEG2000-Cy5 supports cell membrane modification, in vivo tumor targeting research and long-term in vivo circulation of its liposomal formulations (Ex/Em=633/670 nm) .

HY-101183

THK5351	Biochemical Assay Reagents
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.

HY-W440913

DSPE-PEG5000-Cy5

Biochemical Assay Reagents

DSPE-PEG-Cy5, MW 5000 is a fluorescently labeled PEGylated phospholipid with a molecular weight of 5000 Da. After intravenous injection, DSPE-PEG-Cy5, MW 5000 shows only extremely low fluorescence accumulation at tumor sites in orthotopic tumor-bearing mice, and can be used as a negative control for evaluating tumor accumulation of nanoparticles. DSPE-PEG-Cy5, MW 5000 can serve as a fluorescent marker to prepare Cy5-labeled NPs-DPPA and NPs-DPPA (C3F8) for pharmacokinetic and biodistribution studies in mice. DSPE-PEG-Cy5, MW 5000 is widely applicable to research in fields related to triple-negative breast cancer, hepatocellular carcinoma and so on .

HY-160276

DOPE-PEG5000-Fluor 555	Biochemical Assay Reagents
DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.

HY-101183R

THK5351 (Standard)	Biochemical Assay Reagents
THK5351 (Standard) is the analytical standard of THK5351 (HY-101183). This product is intended for research and analytical applications. THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.

Cat. No.	Product Name	Target	Research Area

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a fluorescein-conjugated peptide that facilitates the targeted delivery of a fluorescent moiety (5-FAM (HY-66022)) to nerves after intravenous (IV) administration. Bevonescein binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves (Ex/Em = 480/530 nm) .

HY-P10943

APO-15	Fluorescent Dye	Inflammation/Immunology Cancer
APO-15 is a phosphatidylserine-binding fluorescent probe and apoptosis imaging reagent. APO-15 exhibits high chemical stability under proteolytic and oxidative conditions, enables quantification and imaging of drug-induced apoptosis in preclinical mouse models, and is applicable to fixed tissue samples and multiple in vivo administration routes (Ex = 488 nm; Em = 525 nm). APO-15 can be used in studies related to acute lung injury and breast cancer .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-P11057

FGGH	Fluorescent Dye	Others
FGGH is a water-soluble peptide-based probe. FGGH performs the sequential detection of Cu ²⁺ and S ^2- by fluorescence and colorimetry with high sensitivity (LOD: 1.42 and 22.2 nM for Cu ²⁺ and S ^2-, respectively) (Ex=488 nm, Em=525 nm), and images both two ions in living cells and zebrafish models with low cytotoxicity. FGGH can be used for in vivo imaging and environmental pollution monitoring research .

HY-P5114A

Maurocalcine TFA	Calcium Channel	Others
Maurocalcine TFA is an agonist of ryanodine receptor (RyR) channel types 1, 2 and 3 with cellular permeability. Maurocalcine TFA induces [ ³H]ryanodine binding on RyR1 with an EC₅₀ value of 2558 nM. Maurocalcine TFA exhibits a apparent affinity of 14 nM for RyR2. Maurocalcine TFA can be applied to in vivo cell tracking or other cell imaging techniques .

HY-P2336

CCZ01048	Melanocortin Receptor	Cancer
CCZ01048, a α-melanocyte-stimulating hormone (α-MSH) analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 is a promising candidate for PET imaging of malignant melanoma .

HY-P11263

AVLX-144	iGluR	Neurological Disease
AVLX-144 is a highly potent inhibitor of postsynaptic density protein 95 (PSD-95). AVLX-144 can be used as a template to develop imaging probes for postsynaptic density (PSD) molecules, and can be labeled with fluorine-18 (¹⁸F) or tritium (³H) to visualize PSD-95 in vivo. AVLX-144 can be utilized for the study of Parkinson's disease .

HY-13443F2

Exendin-4, Cy5 labeled Exendin-4-Cys(Cy5)	Fluorescent Dye	Metabolic Disease
Exendin-4, Cy5-labeled (Exendin-4-Cys(Cy5)) is a covalently linked Cy5 fluorescent group to Exendin-4 (HY-13443), a GLP-1 receptor agonist. Exendin-4, Cy5-labeled enables the visualization imaging of β cells in vivo, especially for evaluating the expression dynamics of GLP-1R in type 2 diabetes models .

HY-P5520

GB-6	Bombesin Receptor Radionuclide-Drug Conjugates (RDCs)	Cancer
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .

HY-P5114

Maurocalcine	Calcium Channel	Others
Maurocalcine is an agonist of ryanodine receptor (RyR) channel types 1, 2 and 3 with cellular permeability. Maurocalcine induces [ ³H]ryanodine binding on RyR1 with an EC₅₀ value of 2558 nM. Maurocalcine exhibits a apparent affinity of 14 nM for RyR2. Maurocalcine can be applied to in vivo cell tracking or other cell imaging techniques .

HY-P10989

NG2 binding peptide	Peptides	Cancer
NG2 binding peptide is a short peptide that specifically recognizes NG2 proteoglycan and can be obtained by phage screening technology. NG2 binding peptide interacts with NG2 binding sites to achieve precise targeting of tumor angiogenesis in vitro and in vivo. NG2 binding peptide exhibits significant homing ability in wild-type tumor-bearing mice, but has no localization effect in NG2 knockout mice. Due to the tissue specificity of NG2 expression, NG2 binding peptide can be used in scenarios such as tumor targeted therapy, drug delivery, and molecular imaging diagnosis .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991577

DS-8895 DS-8895A	Ephrin Receptor	Cancer
DS-8895(DS-8895A) is an anti-EphA2 monoclonal antibody with specific binding to EphA2 receptors and EphA2-expressing cells. DS-8895, when conjugated with ⁸⁹Zr, ¹¹¹In, or ¹²⁵I, supports molecular imaging of EphA2 expression in xenograft models. DS-8895 allows noninvasive measurement of EphA2 expresssion in tumors in vivo. .

HY-P991319

TAB-004	Inhibitory Antibodies	Cancer
TAB-004 is a murine IgG1 monoclonal antibody that specifically binds to the tumor-associated hypoglycosylated mucin 1 (tMUC1), with high selectivity for human tMUC1. TAB-004 can be conjugated with Indocyanine green (ICG) (HY-D0711) for in vivo targeted imaging. TAB-004 can be used for the research of early detection, tumor progression monitoring and cancer stem cell targeting in breast cancer and pancreatic cancer.

HY-P992367

hIMB1636	TROP2	Cancer
hIMB1636 is a humanized monoclonal antibody targeting Trop2. By binding to the conformational Trop2 epitope, hIMB1636 regulates related signaling pathways, triggers lysosomal endocytosis, and further induces apoptosis, cell cycle arrest, and antibody-dependent cellular cytotoxicity. hIMB1636 effectively inhibits tumor cell proliferation, migration and in vivo tumor growth, and also exerts bystander killing effect and mediates long-term retention. hIMB1636 can be conjugated with NOTA/DOTA for radiolabeling to enable immuno-PET imaging, or prepared as hIMB1636-LDP-AE to significantly inhibit the growth of breast cancer and lung cancer xenografts .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-165424

NIR-BG2	Alkaloids Other Alkaloids Cananga odorata Plants Annonaceae Indole Alkaloids Source Classification	Fluorescent Dye Glycosidase
NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .

Cat. No.	Product Name	Chemical Structure

HY-B0594S

Iohexol-d5
Iohexol-d₅ is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography?(cisternography, ventriculography) and MicroCT imaging in vivo .

HY-122607S

DPA-714-d10

DPA-714-d₁₀ is the deuterium labeled DPA-714 (HY-122607). DPA-714 is a high affinity translocator protein (TSPO) ligand (K_i=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. ¹⁸FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model.

Cat. No.	Product Name		Classification

HY-D1583

Cyanine5 DBCO hexafluorophosphate 3 Publications Verification DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate		DBCO
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .

HY-D1557

Cyanine5.5 tetrazine		Labeling and Fluorescence Imaging Tetrazine
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D2217

Cy7 tetrazine		Tetrazine
Cy7 tetrazine is a near infrared dye that can be used for in vivo imaging .

Cat. No.	Product Name		Classification

HY-W440911

DSPE-PEG2000-Cy5		Pegylated Lipids Fluorescent Lipids
DSPE-PEG2000-Cy5 is a Cy5 (HY-D0821) fluorophore-labeled conjugate of distearoylphosphatidylethanolamine and polyethylene glycol, as well as a liposome component. The Cy5 fluorophore is commonly used for labeling proteins and nucleic acids in imaging, flow cytometry and genomic applications. DSPE-PEG2000-Cy5 supports cell membrane modification, in vivo tumor targeting research and long-term in vivo circulation of its liposomal formulations (Ex/Em=633/670 nm) .

HY-171493

mCherry mRNA(N1-Me-Pseudo UTP)		mRNA
mCherry mRNA(N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression analysis, cell viability assays, and in vivo imaging. mCherry, derived from mushroom coral, is a widely used red fluorescent protein tracer in biotechnology applications.

HY-118667

Dehydroergosterol 1 Publications Verification		Cholesterol
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .

HY-W440913

DSPE-PEG5000-Cy5		Pegylated Lipids Fluorescent Lipids
DSPE-PEG-Cy5, MW 5000 is a fluorescently labeled PEGylated phospholipid with a molecular weight of 5000 Da. After intravenous injection, DSPE-PEG-Cy5, MW 5000 shows only extremely low fluorescence accumulation at tumor sites in orthotopic tumor-bearing mice, and can be used as a negative control for evaluating tumor accumulation of nanoparticles. DSPE-PEG-Cy5, MW 5000 can serve as a fluorescent marker to prepare Cy5-labeled NPs-DPPA and NPs-DPPA (C3F8) for pharmacokinetic and biodistribution studies in mice. DSPE-PEG-Cy5, MW 5000 is widely applicable to research in fields related to triple-negative breast cancer, hepatocellular carcinoma and so on .

HY-160276

DOPE-PEG5000-Fluor 555		Pegylated Lipids Fluorescent Lipids
DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.

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