3 Results for "

wfs1abKO zebrafish larvae

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "wfs1abKO zebrafish larvae" in MCE Product Catalog:

Cat. No.: HY-N15339
CAS No.: 500-56-1
Convolamine is a tropane alkaloid and a potent Sigma-1 receptor positive allosteric modulator with an IC50 value of 289 nM. Convolamine can be extracted from Convolvulus plauricalis. Convolamine exhibits cognitive-improving and neuroprotective properties. Convolamine can be used in research related to Wolfram syndrome and Alzheimer's disease .
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Cat. No.: HY-181649
CAS No.: 401501-66-4
Target:  

Sigma Receptor

Research Areas:  

Neurological Disease

S1R agonist 3 is a potent, selective and brain-penetrant sigma-1 receptor (S1R) agonist with a Ki of 1.5 nM. S1R agonist 3 reduces hyperlocomotion in wfs1abKO zebrafish larvae without affecting locomotion in wildtype wfs1abWT zebrafish larvae. S1R agonist 3 reverses Aβ25-35 (HY-P0128)-induced learning and memory impairments. S1R ligand 1 can be used for the research of Alzheimer’s disease .
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Cat. No.: HY-N15339A
CAS No.: 5896-59-3
Convolamine hydrochloride is a tropane alkaloid and a potent Sigma-1 receptor positive allosteric modulator with an IC50 value of 289 nM. Convolamine hydrochloride can be extracted from Convolvulus plauricalis. Convolamine hydrochloride exhibits cognitive-improving and neuroprotective properties. Convolamine hydrochloride can be used in research related to Wolfram syndrome and Alzheimer's disease .
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