2. Protein Tyrosine Kinase/RTK
  3. SHP2
  4. SHP2-IN-27

SHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase SH2.

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SHP2-IN-27

SHP2-IN-27 화학구조

CAS No. : 2376012-00-7

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SHP2-IN-27 Related Antibodies

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제품 설명

SHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase SH2[1].

Cellular Effect
Cell Line Type Value Description References
HCC827 IC50
2.1 μM
Compound: 28
Antiproliferative activity against human HCC827 cells harboring EGFR del 746 to 750 mutant assessed as inhibition of cell growth incubated for 6 days by celltiter-glo luminescence based analysis
Antiproliferative activity against human HCC827 cells harboring EGFR del 746 to 750 mutant assessed as inhibition of cell growth incubated for 6 days by celltiter-glo luminescence based analysis
[PMID: 38462716]
분자량

407.90

화학식

C21H22ClN7
CAS No.
SMILES

N[C@H](C[C@@H]1CC2)C[C@@H]2N1C3=CN=C4C(NC=C4C5=C(Cl)C6=CN(C)N=C6C=C5)=N3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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SHP2-IN-27 Related Classifications

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Keywords:

SHP2-IN-272376012-00-7SHP2Src homology phosphatase 2PTPN11Inhibitorinhibitorinhibit

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상품명:
SHP2-IN-27
Cat. No.:
HY-162355
수량:
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