1. GPCR/G Protein
    Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. Spexin

Spexin (Synonyms: Neuropeptide Q)

Cat. No.: HY-P1723
Handling Instructions

Spexin is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Spexin exhibits no significant activity at galanin receptor 1. Spexin is an endogenous satiety-inducing peptide; Spexin inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Spexin attenuates LH secretion in goldfish. Spexin exhibits anxiolytic effects in vivo.

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Spexin Chemical Structure

Spexin Chemical Structure

CAS No. : 1370290-58-6

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Description

Spexin is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Spexin exhibits no significant activity at galanin receptor 1. Spexin is an endogenous satiety-inducing peptide; Spexin inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Spexin attenuates LH secretion in goldfish. Spexin exhibits anxiolytic effects in vivo.

Molecular Weight

1619.88

Formula

C₇₄H₁₁₄N₂₀O₁₉S

CAS No.

1370290-58-6

Sequence

{Asn}{Trp}{Thr}{Pro}{Gln}{Ala}{Met}{Leu}{Tyr}{Leu}{Lys}{Gly}{Ala}{Gln}-NH2

Sequence Shortening

NWTPQAMLYLKGAQ-NH2

SMILES

[NWTPQAMLYLKGAQ-NH2]

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Keywords:

SpexinNeuropeptide QNeuropeptide Y ReceptorNPY receptorInhibitorinhibitorinhibit

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