1. GPCR/G Protein Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. Velneperit

Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist.

For research use only. We do not sell to patients.

Velneperit Chemical Structure

Velneperit Chemical Structure

CAS No. : 342577-38-2

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 99 In-stock
Solution
10 mM * 1 mL in DMSO USD 99 In-stock
Solid
5 mg USD 90 In-stock
10 mg USD 150 In-stock
25 mg USD 330 In-stock
50 mg USD 560 In-stock
100 mg USD 950 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Velneperit

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist. Target: neuropeptide Y receptor Velneperit (S-2367) is a once-daily, oral, centrally acting, small molecule neuropeptide Y (NPY) Y5 receptor antagonist.

Clinical Trial
Molecular Weight

407.45

Formula

C17H24F3N3O3S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC(F)(F)C1=CN=C(NC([C@H]2CC[C@H](NS(=O)(C(C)(C)C)=O)CC2)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (73.63 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4543 mL 12.2714 mL 24.5429 mL
5 mM 0.4909 mL 2.4543 mL 4.9086 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4543 mL 12.2714 mL 24.5429 mL 61.3572 mL
5 mM 0.4909 mL 2.4543 mL 4.9086 mL 12.2714 mL
10 mM 0.2454 mL 1.2271 mL 2.4543 mL 6.1357 mL
15 mM 0.1636 mL 0.8181 mL 1.6362 mL 4.0905 mL
20 mM 0.1227 mL 0.6136 mL 1.2271 mL 3.0679 mL
25 mM 0.0982 mL 0.4909 mL 0.9817 mL 2.4543 mL
30 mM 0.0818 mL 0.4090 mL 0.8181 mL 2.0452 mL
40 mM 0.0614 mL 0.3068 mL 0.6136 mL 1.5339 mL
50 mM 0.0491 mL 0.2454 mL 0.4909 mL 1.2271 mL
60 mM 0.0409 mL 0.2045 mL 0.4090 mL 1.0226 mL
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Velneperit Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Velneperit
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HY-14423
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