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SPOP-IN-6b hydrochloride 

Cat. No.: HY-122615A
Handling Instructions

SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.

For research use only. We do not sell to patients.

SPOP-IN-6b hydrochloride Chemical Structure

SPOP-IN-6b hydrochloride Chemical Structure

CAS No. : 2136270-68-1

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Description

SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM[1].

In Vitro

SPOP-IN-6b shows IC50s of 2-10.2 μM for A498、Caki-2、Ketr-3,769-P,0S-RC-2 and 786-0 cells[1].
SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

537.05

Formula

C₂₈H₃₃ClN₆O₃

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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SPOP-IN-6b hydrochloride
Cat. No.:
HY-122615A
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