Sulfisoxazole acetyl
Based on 1 Customer Validation
Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase inhibitor. Sulfisoxazole acetyl has an antibacterial action.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 80-74-0
- Formula: C13H15N3O4S
- Molecular Weight:309.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
As with other sulfonamides, the antibacterial action of Sulfisoxazole acetyl (N1-Acetylsulfisoxazole) is attributable to inhibiting dihydropteroate synthase, a key enzyme in folate synthesis in bacteria. Sulfisoxazole acetyl is known to be transformed primarily to sulfisoxazole, partly to N4-acetyl sulfisoxazole (N4AS), and likely also to diacetyl sulfisoxazole (DAS) and other compounds[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 80-74-0
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Appearance Solid
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Molecular Weight 309.34
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Formula C13H15N3O4S
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Color White to off-white
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SMILES
O=C(C)N(S(=O)(C1=CC=C(C=C1)N)=O)C2=C(C)C(C)=NO2
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Synonyms
N1-Acetylsulfisoxazole
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (808.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2327 mL | 16.1634 mL | 32.3269 mL | 80.8172 mL |
| 5 mM | 0.6465 mL | 3.2327 mL | 6.4654 mL | 16.1634 mL | |
| 10 mM | 0.3233 mL | 1.6163 mL | 3.2327 mL | 8.0817 mL | |
| 15 mM | 0.2155 mL | 1.0776 mL | 2.1551 mL | 5.3878 mL | |
| 20 mM | 0.1616 mL | 0.8082 mL | 1.6163 mL | 4.0409 mL | |
| 25 mM | 0.1293 mL | 0.6465 mL | 1.2931 mL | 3.2327 mL | |
| 30 mM | 0.1078 mL | 0.5388 mL | 1.0776 mL | 2.6939 mL | |
| 40 mM | 0.0808 mL | 0.4041 mL | 0.8082 mL | 2.0204 mL | |
| 50 mM | 0.0647 mL | 0.3233 mL | 0.6465 mL | 1.6163 mL | |
| 60 mM | 0.0539 mL | 0.2694 mL | 0.5388 mL | 1.3470 mL | |
| 80 mM | 0.0404 mL | 0.2020 mL | 0.4041 mL | 1.0102 mL | |
| 100 mM | 0.0323 mL | 0.1616 mL | 0.3233 mL | 0.8082 mL |