2. Neuronal Signaling
  3. Amyloid-β
  4. ACI-19626

ACI-19626 (TDP-43-IN-2) is a TDP-43 aggregation inhibitor that can be used in the research of neurodegenerative diseases.

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ACI-19626

ACI-19626 화학구조

CAS No. : 3033951-93-5

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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ACI-19626 Related Antibodies

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제품 설명

ACI-19626 (TDP-43-IN-2) is a TDP-43 aggregation inhibitor that can be used in the research of neurodegenerative diseases[1][2].

In Vitro

ACI-19626 (compound 17) inhibits TDP-43 aggregates with a Ki value of 22 nM[1].
[18F]ACI-19626 can serve as a PET imaging agent for TDP-43 pathology[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ACI-19626 Related Antibodies
분자량

439.51

화학식

C22H22FN5O2S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(CCN1C3=CC=CN=C3)N=C(C4=C(F)N=C(N5CCC(CC5)CO)C=C4)S2
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 5 mg/mL (11.38 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2753 mL 11.3763 mL 22.7526 mL
5 mM 0.4551 mL 2.2753 mL 4.5505 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2753 mL 11.3763 mL 22.7526 mL 56.8815 mL
5 mM 0.4551 mL 2.2753 mL 4.5505 mL 11.3763 mL
10 mM 0.2275 mL 1.1376 mL 2.2753 mL 5.6882 mL
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ACI-19626 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACI-196263033951-93-5TDP-43-IN-2ACI19626ACI 19626Amyloid-ββ-amyloid peptideAβAbetamyotrophic lateral sclerosisAlzheimer’s diseaseFrontotemporal dementiaInhibitorinhibitorinhibit

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Inquiry Information

상품명:
ACI-19626
Cat. No.:
HY-163575
수량:
MCE Japan Authorized Agent:

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