Tenofovir alafenamide-d5 fumarate
Tenofovir alafenamide-d5 fumarate (GS-7340-d5 fumarate) is the deuterium labeled Tenofovir alafenamide fumarate (HY-15232A). Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
For research use only. We do not sell to patients.
- Formula: C25H28D5N6O9P
- Molecular Weight:597.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 379270-38-9
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Molecular Weight 597.57
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Formula C25H28D5N6O9P
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SMILES
OC(/C=C/C(O)=O)=O.CC(C)OC([C@H](C)NP(CO[C@H](C)CN1C2=NC=NC(N)=C2N=C1)(OC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O)=O
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Synonyms
GS-7340-d5 fumarate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)