2. PROTAC Autophagy Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis
  4. Thalidomide-4-O-C3-NH2 hydrochloride

Thalidomide-4-O-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

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Thalidomide-4-O-C3-NH2 hydrochloride

Thalidomide-4-O-C3-NH2 hydrochloride Estructura química

No. CAS : 2913240-95-4

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100 mg Pide un presupuesto y un plazo de entrega
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1 g Pide un presupuesto y un plazo de entrega

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Other Forms of Thalidomide-4-O-C3-NH2 hydrochloride:

Thalidomide-4-O-C3-NH2 hydrochloride Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas E3 Ligase Ligand-Linker Conjugates:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Descripciòn

Thalidomide-4-O-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thalidomide-4-O-C3-NH2 hydrochloride Related Antibodies
Peso molecular

367.78

Fòrmula

C16H18ClN3O5
No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCCN)=O.[H]Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Pureza y Documentación
Referencias
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Thalidomide-4-O-C3-NH2 hydrochloride Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-4-O-C3-NH22913240-95-4E3 Ligase Ligand-Linker ConjugatesAutophagyApoptosisInhibitorinhibitorinhibit

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Nombre del producto:
Thalidomide-4-O-C3-NH2 hydrochloride
Cat. No.:
HY-138847A
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