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Thalidomide-NH-(CH2)2-NH-Boc

Thalidomide-NH-(CH2)2-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)2-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)2-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

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  • CAS No.: 1957235-57-2
  • Formula: C20H24N4O6
  • Molecular Weight:416.43
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Thalidomide-NH-(CH2)2-NH-Boc Chemical Structure
    Thalidomide-NH-(CH2)2-NH-Boc Chemical Structure
CAS No.: 1957235-57-2
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Use of MCE Products

All E3 Ligase Ligand-Linker Conjugates Isoforms

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  • Thalidomide-NH-(CH2)2-NH-Boc Chemical Structure
    Thalidomide-NH-(CH2)2-NH-Boc Chemical Structure
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  • Thalidomide-NH-(CH2)2-NH-Boc