2. Immunology/Inflammation
  3. Tim3
  4. TIM-3-IN-1

TIM-3-IN-1 (Compound 38) is a TIM-3 inhibitor that can be used for the research of cancer.

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TIM-3-IN-1

TIM-3-IN-1 Chemische Struktur

CAS. Nr. : 2883237-04-3

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
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Based on 1 publication(s) in Google Scholar

TIM-3-IN-1 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE TIM-3-IN-1

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Beschreibung

TIM-3-IN-1 (Compound 38) is a TIM-3 inhibitor that can be used for the research of cancer[1].

Molekulargewicht

469.90

Formel

C20H16ClN7O3S
CAS. Nr.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CC1=NN2C(NC3=CC(Cl)=C(C4=C(C)C=C(NS(C5=NC=CN5)(=O)=O)C=C4)C=C3C2=N1)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (212.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1281 mL 10.6406 mL 21.2811 mL
5 mM 0.4256 mL 2.1281 mL 4.2562 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 98.90%

SDS (251 KB)

COA (252 KB) HNMR (128 KB) LCMS (100 KB)

Handling Instructions (2659 KB)
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1281 mL 10.6406 mL 21.2811 mL 53.2028 mL
5 mM 0.4256 mL 2.1281 mL 4.2562 mL 10.6406 mL
10 mM 0.2128 mL 1.0641 mL 2.1281 mL 5.3203 mL
15 mM 0.1419 mL 0.7094 mL 1.4187 mL 3.5469 mL
20 mM 0.1064 mL 0.5320 mL 1.0641 mL 2.6601 mL
25 mM 0.0851 mL 0.4256 mL 0.8512 mL 2.1281 mL
30 mM 0.0709 mL 0.3547 mL 0.7094 mL 1.7734 mL
40 mM 0.0532 mL 0.2660 mL 0.5320 mL 1.3301 mL
50 mM 0.0426 mL 0.2128 mL 0.4256 mL 1.0641 mL
60 mM 0.0355 mL 0.1773 mL 0.3547 mL 0.8867 mL
80 mM 0.0266 mL 0.1330 mL 0.2660 mL 0.6650 mL
100 mM 0.0213 mL 0.1064 mL 0.2128 mL 0.5320 mL
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TIM-3-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TIM-3-IN-12883237-04-3Tim3T-Cell Immunoglobulin and Mucin Containing Protein-3CD366cancerInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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