Trifluoroacetyl tripeptide-2
Based on 1 Customer Validation
Trifluoroacetyl tripeptide-2 is a tripeptide with strong cosmetic activity. Trifluoroacetyl tripeptide-2 can regulate progerin synthesis, promote extracellular matrix synthesis, and improve skin elasticity. Trifluoroacetyl tripeptide-2 has anti-wrinkle and firming effects and can be used as an anti-aging ingredient in cosmetic research.
For research use only. We do not sell to patients.
- Purity: 98.71%
- CAS No.: 64577-63-5
- Formula: C21H28F3N3O6
- Molecular Weight:475.46
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Trifluoroacetyl tripeptide-2 (0.1 mg/mL; 24 h; in the form of hydrogel) shows permeability in pig ear skin[2].
Trifluoroacetyl tripeptide-2 (1 mg; 24-48 h) has no significant effect on the viability of human immortalized keratinocyte HaCaT[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HaCaT cells
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Concentration:1 mg
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Incubation Time:24 and 48 h
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Result:Had no significant effect on the cell viability and the cells continue to proliferate after 48 h.
Chemical Information
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CAS No. 64577-63-5
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Appearance Solid
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Molecular Weight 475.46
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Formula C21H28F3N3O6
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Color White to off-white
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Sequence
{Tfa}-Val-Tyr-Val
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Sequence Shortening
{Tfa}-VYV
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 175 mg/mL (368.06 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1032 mL | 10.5161 mL | 21.0323 mL | 52.5807 mL |
| 5 mM | 0.4206 mL | 2.1032 mL | 4.2065 mL | 10.5161 mL | |
| 10 mM | 0.2103 mL | 1.0516 mL | 2.1032 mL | 5.2581 mL | |
| 15 mM | 0.1402 mL | 0.7011 mL | 1.4022 mL | 3.5054 mL | |
| 20 mM | 0.1052 mL | 0.5258 mL | 1.0516 mL | 2.6290 mL | |
| 25 mM | 0.0841 mL | 0.4206 mL | 0.8413 mL | 2.1032 mL | |
| 30 mM | 0.0701 mL | 0.3505 mL | 0.7011 mL | 1.7527 mL | |
| 40 mM | 0.0526 mL | 0.2629 mL | 0.5258 mL | 1.3145 mL | |
| 50 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 1.0516 mL | |
| 60 mM | 0.0351 mL | 0.1753 mL | 0.3505 mL | 0.8763 mL | |
| 80 mM | 0.0263 mL | 0.1315 mL | 0.2629 mL | 0.6573 mL | |
| 100 mM | 0.0210 mL | 0.1052 mL | 0.2103 mL | 0.5258 mL |