1173023-85-2
Chemical Structure
GW583340 dihydrochloride
- CAS No.: 1173023-85-2
- Formula:C28H27Cl3FN5O3S2
- Molecular Weight:671.03
IUPAC Name: N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(2-(((2-(methylsulfonyl)ethyl)amino)methyl)thiazol-4-yl)quinazolin-4-amine dihydrochloride
InChIKey: WIMITXDBYLKRKB-UHFFFAOYSA-N
SMILES: O=S(CCNCC1=NC(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)=CS1)(C)=O.Cl.Cl
Biological Activity: GW 583340 dihydrochloride is an orally active ErbB-2/EGFR tyrosine kinase inhibitor. GW 583340 dihydrochloride exhibits antitumor activity in xenograft models with EGFR overexpression or ErbB-2 overexpression. GW 583340 dihydrochloride is applicable to research related to head and neck cancer, breast cancer, and gastric cancer[1].
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GW583340 dihydrochloride | GW 583340 dihydrochloride is an orally active ErbB-2/EGFR tyrosine kinase inhibitor. GW 583340 dihydrochloride exhibits antitumor activity in xenograft models with EGFR overexpression or ErbB-2 overexpression. GW 583340 dihydrochloride is applicable to research related to head and neck cancer, breast cancer, and gastric cancer. | |||||||||||||||||||||
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