OTX1 - orthodenticle homeobox 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5013

About OTX1

Cytogenetic location: 2p15 Genomic coordinates (GRCh38): 2:63,049,735-63,057,831 (from NCBI)

This gene has 6 transcripts (splice variants), 197 orthologues and 50 paralogues. Biased expression in skin (RPKM 2.2), prostate (RPKM 0.7) and 5 other tissues.

Summary

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

OTX1 Products (2)

mRNA Protein Name
NM_001199770.2 NP_001186699.1 homeobox protein OTX1
NM_014562.4 NP_055377.1 homeobox protein OTX1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18849347 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18849347 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18849347 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OTX1 Protein Structure

Homeobox

Homeobox: Homeobox domain (39 - 95)

TF_Otx

TF_Otx: Otx1 transcription factor (178 - 280)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
Protein Preferred Names Protein Names

homeobox protein OTX1

  • orthodenticle homolog 1

OTX1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
OTX1 P32242 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP10-8 Homo sapiens P60410
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP10-8 Homo sapiens P60410
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 KRTAP10-9 Homo sapiens P60411
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP10-9 Homo sapiens P60411
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP10-9 Homo sapiens P60411
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP10-5 Homo sapiens P60370
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP10-5 Homo sapiens P60370
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP10-7 Homo sapiens P60409
Validated Y2H
32296183
Intra
OTX1 P32242 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ADAMTSL4 Homo sapiens Q6UY14-3
Validated Y2H
32296183
Intra
OTX1 P32242 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP12-2 Homo sapiens P59991
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP12-2 Homo sapiens P59991
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP12-2 Homo sapiens P59991
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP12-2 Homo sapiens P59991
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP12-4 Homo sapiens P60329
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP12-4 Homo sapiens P60329
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP12-4 Homo sapiens P60329
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 RGS20 Homo sapiens O76081-6
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 RGS20 Homo sapiens O76081-6
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP9-4 Homo sapiens Q9BYQ2
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 KRTAP9-4 Homo sapiens Q9BYQ2
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP12-1 Homo sapiens P59990
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP12-1 Homo sapiens P59990
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP12-1 Homo sapiens P59990
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP10-11 Homo sapiens P60412
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP10-11 Homo sapiens P60412
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP10-11 Homo sapiens P60412
Y2H Array
25416956
Intra
OTX1 P32242 KRT83 Homo sapiens P78385
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP13-3 Homo sapiens Q3SY46
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP13-3 Homo sapiens Q3SY46
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP13-3 Homo sapiens Q3SY46
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP19-7 Homo sapiens Q3SYF9
Validated Y2H
32296183
Intra
OTX1 P32242 LCE1B Homo sapiens Q5T7P3
Y2H Array
31515488
Intra
OTX1 P32242 LCE1B Homo sapiens Q5T7P3
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 LCE1B Homo sapiens Q5T7P3
Y2H Array
29892012
Intra
OTX1 P32242 LCE4A Homo sapiens Q5TA78
Y2H Array
25416956
Intra
OTX1 P32242 LCE4A Homo sapiens Q5TA78
Validated Y2H
25416956
Intra
OTX1 P32242 LCE4A Homo sapiens Q5TA78
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 LCE2A Homo sapiens Q5TA79
Y2H Array
25416956
Intra
OTX1 P32242 LCE2D Homo sapiens Q5TA82
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 LCE2D Homo sapiens Q5TA82
Validated Y2H
32296183
Intra
OTX1 P32242 LCE2D Homo sapiens Q5TA82
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP5-6 Homo sapiens Q6L8G9
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP5-6 Homo sapiens Q6L8G9
Validated Y2H
25416956
Intra
OTX1 P32242 KCNK16 Homo sapiens Q96T55
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP4-11 Homo sapiens Q9BYQ6
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP4-11 Homo sapiens Q9BYQ6
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP9-3 Homo sapiens Q9BYQ3
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP9-3 Homo sapiens Q9BYQ3
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP9-3 Homo sapiens Q9BYQ3
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 KRTAP9-2 Homo sapiens Q9BYQ4
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP9-2 Homo sapiens Q9BYQ4
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Array
25416956
Intra
OTX1 P32242 KRT37 Homo sapiens O76014
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRT37 Homo sapiens O76014
Y2H Array
32296183
Intra
OTX1 P32242 KRT85 Homo sapiens P78386
Validated Y2H
32296183
Intra
OTX1 P32242 KRT85 Homo sapiens P78386
Y2H Array
32296183
Intra
OTX1 P32242 KRT85 Homo sapiens P78386
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 CCN4 Homo sapiens O95388
Y2H Array
32296183
Intra
OTX1 P32242 CCN4 Homo sapiens O95388
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP11-1 Homo sapiens Q8IUC1
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Array
32296183
Intra
OTX1 P32242 RGS20 Homo sapiens O76081
Y2H
21516116
Intra
OTX1 P32242 RGS20 Homo sapiens O76081
Y2H Array
31515488
Intra
OTX1 P32242 RGS20 Homo sapiens O76081
Validated Y2H
25416956
Intra
OTX1 P32242 RGS20 Homo sapiens O76081
Y2H Array
25416956
Intra
OTX1 P32242 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra
OTX1 P32242 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra
OTX1 P32242 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra
OTX1 P32242 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra
OTX1 P32242 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
Intra
OTX1 P32242 KPRP Homo sapiens Q5T749
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KPRP Homo sapiens Q5T749
Y2H Array
32296183
Intra
OTX1 P32242 KPRP Homo sapiens Q5T749
Validated Y2H
32296183
Intra
OTX1 P32242 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 GPRASP3 Homo sapiens Q6PI77
Validated Y2H
32296183
Intra
OTX1 P32242 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP1-5 Homo sapiens Q9BYS1
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP1-5 Homo sapiens Q9BYS1
Validated Y2H
27107012
Intra
OTX1 P32242 KRTAP1-5 Homo sapiens Q9BYS1
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP1-5 Homo sapiens Q9BYS1
Y2H Array
32296183
Intra
OTX1 P32242 VWC2L Homo sapiens B2RUY7
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP1-3 Homo sapiens Q8IUG1
Validated Y2H
27107012
Intra
OTX1 P32242 KRTAP1-3 Homo sapiens Q8IUG1
BFG-2H
27107012
Intra
OTX1 P32242 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP12-3 Homo sapiens P60328
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP13-2 Homo sapiens Q52LG2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP13-2 Homo sapiens Q52LG2
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP13-2 Homo sapiens Q52LG2
Validated Y2H
32296183
Intra
OTX1 P32242 PCSK5 Homo sapiens Q92824-2
Validated Y2H
32296183
Intra
OTX1 P32242 PCSK5 Homo sapiens Q92824-2
Y2H Array
32296183
Intra
OTX1 P32242 PCSK5 Homo sapiens Q92824-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 VWC2 Homo sapiens Q2TAL6
Validated Y2H
32296183
Intra
OTX1 P32242 LCE1F Homo sapiens Q5T754
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 LCE1F Homo sapiens Q5T754
Y2H Array
32296183
Intra
OTX1 P32242 LCE1F Homo sapiens Q5T754
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP4-4 Homo sapiens Q9BYR3
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP9-8 Homo sapiens Q9BYQ0
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP1-1 Homo sapiens Q07627
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP6-2 Homo sapiens Q3LI66
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP5-4 Homo sapiens Q6L8H1
Validated Y2H
32296183
Intra
OTX1 P32242 LCE2C Homo sapiens Q5TA81
Validated Y2H
32296183
Intra
OTX1 P32242 LCE2C Homo sapiens Q5TA81
Y2H Array
32296183
Intra
OTX1 P32242 LCE2C Homo sapiens Q5TA81
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP5-3 Homo sapiens Q6L8H2
Validated Y2H
32296183
Intra
OTX1 P32242 USP54 Homo sapiens Q70EL1-9
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 USP54 Homo sapiens Q70EL1-9
Validated Y2H
32296183
Intra
OTX1 P32242 USP54 Homo sapiens Q70EL1-9
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP17-1 Homo sapiens Q9BYP8
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP17-1 Homo sapiens Q9BYP8
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP17-1 Homo sapiens Q9BYP8
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP15-1 Homo sapiens Q3LI76
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP4-5 Homo sapiens Q9BYR2
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP4-5 Homo sapiens Q9BYR2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP5-11 Homo sapiens Q6L8G4
Validated Y2H
32296183
Intra
OTX1 P32242 ADAM12 Homo sapiens O43184-4
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ADAM12 Homo sapiens O43184-4
Y2H Array
32296183
Intra
OTX1 P32242 NTM Homo sapiens Q9P121-3
Validated Y2H
32296183
Intra
OTX1 P32242 WWOX Homo sapiens Q9NZC7-5
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 WWOX Homo sapiens Q9NZC7-5
Validated Y2H
32296183
Intra
OTX1 P32242 WWOX Homo sapiens Q9NZC7-5
Y2H Array
32296183
Intra
OTX1 P32242 ANKRD10 Homo sapiens Q9NXR5-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ANKRD10 Homo sapiens Q9NXR5-2
Validated Y2H
32296183
Intra
OTX1 P32242 ANKRD10 Homo sapiens Q9NXR5-2
Y2H Array
32296183
Intra
OTX1 P32242 NECTIN3 Homo sapiens Q9NQS3-2
Validated Y2H
32296183
Intra
OTX1 P32242 NECTIN3 Homo sapiens Q9NQS3-2
Y2H Array
32296183
Intra
OTX1 P32242 NECTIN3 Homo sapiens Q9NQS3-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP6-1 Homo sapiens Q3LI64
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 FAM168B Homo sapiens A1KXE4-2
Y2H Array
32296183
Intra
OTX1 P32242 FAM168B Homo sapiens A1KXE4-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP19-2 Homo sapiens Q3LHN2
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 LCE1C Homo sapiens Q5T751
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 LCE1C Homo sapiens Q5T751
Y2H Array
32296183
Intra
OTX1 P32242 LCE1C Homo sapiens Q5T751
Validated Y2H
32296183
Intra
OTX1 P32242 CERCAM Homo sapiens Q5T4B2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 CERCAM Homo sapiens Q5T4B2
Validated Y2H
32296183
Intra
OTX1 P32242 CERCAM Homo sapiens Q5T4B2
Y2H Array
32296183
Intra
OTX1 P32242 ZBTB42 Homo sapiens B2RXF5
Y2H Array
32296183
Intra
OTX1 P32242 ZBTB42 Homo sapiens B2RXF5
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 SPRYD7 Homo sapiens Q5W111-2
Validated Y2H
32296183
Intra
OTX1 P32242 SPRYD7 Homo sapiens Q5W111-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 SPRYD7 Homo sapiens Q5W111-2
Y2H Array
32296183
Intra
OTX1 P32242 CHRDL2 Homo sapiens Q6WN34-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 CHRDL2 Homo sapiens Q6WN34-2
Validated Y2H
32296183
Intra
OTX1 P32242 CHRDL2 Homo sapiens Q6WN34-2
Y2H Array
32296183
Intra
OTX1 P32242 SLC15A2 Homo sapiens Q16348
Validated Y2H
32296183
Intra
OTX1 P32242 SLC15A2 Homo sapiens Q16348
Y2H Array
32296183
Intra
OTX1 P32242 SLC15A2 Homo sapiens Q16348
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 C10orf55 Homo sapiens Q5SWW7
Y2H Array
32296183
Intra
OTX1 P32242 C10orf55 Homo sapiens Q5SWW7
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 C10orf55 Homo sapiens Q5SWW7
Validated Y2H
32296183
Intra
OTX1 P32242 OXER1 Homo sapiens Q8TDS5
Validated Y2H
32296183
Intra
OTX1 P32242 OXER1 Homo sapiens Q8TDS5
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 OXER1 Homo sapiens Q8TDS5
Y2H Array
32296183
Intra
OTX1 P32242 CH25H Homo sapiens O95992
Y2H Array
32296183
Intra
OTX1 P32242 CH25H Homo sapiens O95992
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ATG9B Homo sapiens Q674R7-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ATG9B Homo sapiens Q674R7-2
Validated Y2H
32296183
Intra
OTX1 P32242 ATG9B Homo sapiens Q674R7-2
Y2H Array
32296183
Intra
OTX1 P32242 NHLRC4 Homo sapiens P0CG21
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 NHLRC4 Homo sapiens P0CG21
Y2H Array
32296183
Intra
OTX1 P32242 FAM72B Homo sapiens Q86X60-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 FAM72B Homo sapiens Q86X60-2
Validated Y2H
32296183
Intra
OTX1 P32242 FAM72B Homo sapiens Q86X60-2
Y2H Array
32296183
Intra
OTX1 P32242 NDUFAF6 Homo sapiens Q330K2-3
Validated Y2H
32296183
Intra
OTX1 P32242 NDUFAF6 Homo sapiens Q330K2-3
Y2H Array
32296183
Intra
OTX1 P32242 NDUFAF6 Homo sapiens Q330K2-3
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP2-4 Homo sapiens Q9BYR9
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP7-1 Homo sapiens Q8IUC3
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP7-1 Homo sapiens Q8IUC3
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP7-1 Homo sapiens Q8IUC3
Validated Y2H
32296183
Intra
OTX1 P32242 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP6-3 Homo sapiens Q3LI67
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP6-3 Homo sapiens Q3LI67
Y2H Array
32296183
Intra
OTX1 P32242 UBAP2 Homo sapiens Q5T6F2
Validated Y2H
32296183
Intra
OTX1 P32242 UBAP2 Homo sapiens Q5T6F2
Y2H Array
32296183
Intra
OTX1 P32242 COMP Homo sapiens P49747
Validated Y2H
32296183
Intra
OTX1 P32242 COMP Homo sapiens P49747
Y2H Array
31515488
Intra
OTX1 P32242 COMP Homo sapiens P49747
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 MIIP Homo sapiens Q5JXC2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 MIIP Homo sapiens Q5JXC2
Validated Y2H
32296183
Intra
OTX1 P32242 MIIP Homo sapiens Q5JXC2
Y2H Array
32296183
Intra
OTX1 P32242 ETFDH Homo sapiens Q16134
Validated Y2H
32296183
Intra
OTX1 P32242 ETFDH Homo sapiens Q16134
Y2H Array
32296183
Intra
OTX1 P32242 ETFDH Homo sapiens Q16134
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP4-1 Homo sapiens Q9BYQ7
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP4-1 Homo sapiens Q9BYQ7
Y2H Array
32296183
Intra
OTX1 P32242 SPRY4 Homo sapiens Q9C004
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 SPRY4 Homo sapiens Q9C004
Validated Y2H
32296183
Intra
OTX1 P32242 SPRY4 Homo sapiens Q9C004
Y2H Array
32296183
Intra
OTX1 P32242 SMARCC1 Homo sapiens Q92922
Validated Y2H
25416956
Intra
OTX1 P32242 TARDBP Homo sapiens Q13148
Validated Y2H
32814053
Intra
OTX1 P32242 TARDBP Homo sapiens Q13148
Y2H Array
32814053
Intra
OTX1 P32242 TARDBP Homo sapiens Q13148
Y2H Pooling
32814053
Intra
OTX1 P32242 ZNF330 Homo sapiens Q9Y3S2
Validated Y2H
32296183
Intra
OTX1 P32242 SPRY1 Homo sapiens O43609
Y2H Array
25416956
Intra
OTX1 P32242 SPRY1 Homo sapiens O43609
Validated Y2H
25416956
Intra
OTX1 P32242 SPRY1 Homo sapiens O43609
Y2H Array
31515488
Intra
OTX1 P32242 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
OTX1 P32242 RGS17 Homo sapiens Q9UGC6
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 RGS17 Homo sapiens Q9UGC6
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 RGS17 Homo sapiens Q9UGC6
Validated Y2H
32296183
Intra
OTX1 P32242 RGS17 Homo sapiens Q9UGC6
Y2H Array
32296183
Intra
OTX1 P32242 PLSCR2 Homo sapiens Q9NRY7
Y2H Array
32296183
Intra
OTX1 P32242 PLSCR2 Homo sapiens Q9NRY7
Validated Y2H
32296183
Intra
OTX1 P32242 PLSCR2 Homo sapiens Q9NRY7
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP26-1 Homo sapiens Q6PEX3
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP26-1 Homo sapiens Q6PEX3
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP3-3 Homo sapiens Q9BYR6
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP3-3 Homo sapiens Q9BYR6
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP3-3 Homo sapiens Q9BYR6
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP3-3 Homo sapiens Q9BYR6
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 LGALS13 Homo sapiens Q9UHV8
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 LGALS13 Homo sapiens Q9UHV8
Validated Y2H
32296183
Intra
OTX1 P32242 LGALS13 Homo sapiens Q9UHV8
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP5-9 Homo sapiens P26371
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP5-9 Homo sapiens P26371
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP5-9 Homo sapiens P26371
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 KRTAP5-9 Homo sapiens P26371
Y2H Array
25416956
Intra
OTX1 P32242 KRTAP5-9 Homo sapiens P26371
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
32296183
Intra
OTX1 P32242 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
32296183
Intra
OTX1 P32242 RTN4R Homo sapiens Q9BZR6
Validated Y2H
32296183
Intra
OTX1 P32242 RTN4R Homo sapiens Q9BZR6
Y2H Array
32296183
Intra
OTX1 P32242 RTN4R Homo sapiens Q9BZR6
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 EFEMP1 Homo sapiens Q12805
Validated Y2H
32296183
Intra
OTX1 P32242 NDUFV2 Homo sapiens P19404
Validated Y2H
32814053
Intra
OTX1 P32242 NDUFV2 Homo sapiens P19404
Y2H Pooling
32814053
Intra
OTX1 P32242 NDUFV2 Homo sapiens P19404
Y2H Array
32814053
Intra
OTX1 P32242 CFAP68 Homo sapiens Q9H5F2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 CFAP68 Homo sapiens Q9H5F2
Validated Y2H
32296183
Intra
OTX1 P32242 CFAP68 Homo sapiens Q9H5F2
Y2H Array
32296183
Intra
OTX1 P32242 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
OTX1 P32242 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
OTX1 P32242 MDFI Homo sapiens Q99750
Y2H Array
30886144
Intra
OTX1 P32242 MDFI Homo sapiens Q99750
BFG-2H
27107012
Intra
OTX1 P32242 MDFI Homo sapiens Q99750
Y2H Pooling
19447967
Intra
OTX1 P32242 KLHL26 Homo sapiens Q53HC5
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KLHL26 Homo sapiens Q53HC5
Validated Y2H
32296183
Intra
OTX1 P32242 KLHL26 Homo sapiens Q53HC5
Y2H Array
32296183
Intra
OTX1 P32242 PLA2G10 Homo sapiens O15496
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 PLA2G10 Homo sapiens O15496
Y2H Array
32296183
Intra
OTX1 P32242 KRT81 Homo sapiens Q14533
Validated Y2H
25416956
Intra
OTX1 P32242 KRT81 Homo sapiens Q14533
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRT81 Homo sapiens Q14533
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP4-12 Homo sapiens Q9BQ66
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP4-12 Homo sapiens Q9BQ66
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP4-12 Homo sapiens Q9BQ66
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP4-12 Homo sapiens Q9BQ66
Y2H Pooling
16189514
Intra
OTX1 P32242 KRTAP4-12 Homo sapiens Q9BQ66
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP4-12 Homo sapiens Q9BQ66
Y2H Array
25416956
Intra
OTX1 P32242 RBPMS Homo sapiens Q93062
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Intra
OTX1 P32242 RBPMS Homo sapiens Q93062
Y2H Pooling
16189514
Intra
OTX1 P32242 PRR13 Homo sapiens Q9NZ81
Validated Y2H
32296183
Intra
OTX1 P32242 PRR13 Homo sapiens Q9NZ81
Y2H Array
32296183
Intra
OTX1 P32242 PRR13 Homo sapiens Q9NZ81
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 CHIC2 Homo sapiens Q9UKJ5
Y2H Pooling
16189514
Intra
OTX1 P32242 CHIC2 Homo sapiens Q9UKJ5
Validated Y2H
32296183
Intra
OTX1 P32242 CHIC2 Homo sapiens Q9UKJ5
Y2H Array
32296183
Intra
OTX1 P32242 CHIC2 Homo sapiens Q9UKJ5
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 TRIP6 Homo sapiens Q15654
Validated Y2H
32296183
Intra
OTX1 P32242 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 TRIP6 Homo sapiens Q15654
Y2H Array
32296183
Intra
OTX1 P32242 SPRY2 Homo sapiens O43597
Y2H Array
25416956
Intra
OTX1 P32242 SPMIP9 Homo sapiens Q96LM6
Validated Y2H
32296183
Intra
OTX1 P32242 SPMIP9 Homo sapiens Q96LM6
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 SPMIP9 Homo sapiens Q96LM6
Y2H Array
32296183
Intra
OTX1 P32242 COL8A1 Homo sapiens P27658
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 COL8A1 Homo sapiens P27658
Y2H Array
32296183
Intra
OTX1 P32242 GRN Homo sapiens P28799
Y2H Array
31515488
Intra
OTX1 P32242 M1AP Homo sapiens Q8TC57
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 M1AP Homo sapiens Q8TC57
Validated Y2H
32296183
Intra
OTX1 P32242 M1AP Homo sapiens Q8TC57
Y2H Array
32296183
Intra
OTX1 P32242 INTS11 Homo sapiens Q5TA45
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 INTS11 Homo sapiens Q5TA45
Validated Y2H
32296183
Intra
OTX1 P32242 INTS11 Homo sapiens Q5TA45
Y2H Array
32296183
Intra
OTX1 P32242 FHL5 Homo sapiens Q5TD97
Validated Y2H
32296183
Intra
OTX1 P32242 FHL5 Homo sapiens Q5TD97
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 FHL5 Homo sapiens Q5TD97
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Array
31515488
Intra
OTX1 P32242 KRTAP3-2 Homo sapiens Q9BYR7
Validated Y2H
25416956
Intra
OTX1 P32242 KRTAP3-2 Homo sapiens Q9BYR7
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Prey Pooling
25416956
Intra
OTX1 P32242 ARHGEF17 Homo sapiens Q96PE2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ARHGEF17 Homo sapiens Q96PE2
Validated Y2H
32296183
Intra
OTX1 P32242 TSPAN4 Homo sapiens O14817
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 TSPAN4 Homo sapiens O14817
Y2H Array
32296183
Intra
OTX1 P32242 RGS19 Homo sapiens P49795
Validated Y2H
32296183
Intra
OTX1 P32242 RGS19 Homo sapiens P49795
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 RGS19 Homo sapiens P49795
Y2H Array
32296183
Intra
OTX1 P32242 LASP1 Homo sapiens Q14847-2
Validated Y2H
32296183
Intra
OTX1 P32242 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra
OTX1 P32242 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 DNMT3A Homo sapiens Q9Y6K1
Validated Y2H
32296183
Intra
OTX1 P32242 POU2AF1 Homo sapiens Q16633
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 POU2AF1 Homo sapiens Q16633
Validated Y2H
32296183
Intra
OTX1 P32242 POU2AF1 Homo sapiens Q16633
Y2H Array
32296183
Intra
OTX1 P32242 FBLN2 Homo sapiens P98095
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 FBLN2 Homo sapiens P98095
Validated Y2H
32296183
Intra
OTX1 P32242 FBLN2 Homo sapiens P98095
Y2H Array
32296183
Intra
OTX1 P32242 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
OTX1 P32242 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
OTX1 P32242 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Intra
OTX1 P32242 ARID5A Homo sapiens Q03989
Validated Y2H
32296183
Intra
OTX1 P32242 PLEKHG4 Homo sapiens Q58EX7
Y2H Prey Pooling
32296183
Intra
OTX1 P32242 PLEKHG4 Homo sapiens Q58EX7
Y2H Array
32296183
Intra
OTX1 P32242 PLEKHG4 Homo sapiens Q58EX7
Validated Y2H
32296183
Intra
OTX1 P32242 TNS2 Homo sapiens Q63HR2
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP3-1 Homo sapiens Q9BYR8
Validated Y2H
32296183
Intra
OTX1 P32242 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Array
32296183
Intra
OTX1 P32242 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

OTX1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83384 OTX1 Antibody (YA3129) WB Human, Mouse, Rat
HY-P83384A OTX1 Antibody (YA3129)(PBS only) WB Human, Mouse, Rat

Related Diseases

Diseases Alias
Agnathia-Otocephaly Complex

  • Otocephaly

  • Holoprosencephaly-Agnathia

  • Dysgnathia Complex Agnathia-Holoprosencephaly

  • AGOTC

  • Agnathia-Holoprosencephaly-Situs Inversus Syndrome

  • Dysgnathia Complex

  • Agnathia-Holoprosencephaly

  • Cervical Auricle
Epilepsy

  • Epilepsy Syndrome

  • Epileptic Syndrome

  • Epilepsies

  • Symptomatic Epilepsies

  • Post Traumatic Epilepsy

  • Traumatic Epilepsy

  • Traumatic Epileptic

  • Epilepsy Due To Hippocampal Sclerosis

  • Epilepsy With Ammon'S Horn Sclerosis

  • Epilepsy Due To Cortical Dysplasia

  • Epilepsy Due To Neuronal Migration Disorders
Dyslexia
Achromatopsia 7

  • ACHM7

  • Achromatopsia, Type 7
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Autism

  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09879 OTX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20790 Otx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27304 Otx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris OTX1 VGNC VGNC:44193
Rattus norvegicus OTX1 RGD RGD:3237
Mus musculus OTX1 MGD MGI:97450
Bos taurus OTX1 VGNC VGNC:32502
Macaca mulatta OTX1 VGNC VGNC:75726
Others OTX1 NCBI