M1AP - meiosis 1 associated protein Gene

Homo sapiens

Also known as D6Mm5e; SPGF48; C2orf65; SPATA37

Gene ID: 130951 | Gene type: protein coding

About M1AP

Cytogenetic location: 2p13.1 Genomic coordinates (GRCh38): 2:74,557,883-74,648,330 (from NCBI)

This gene has 9 transcripts (splice variants), 174 orthologues and is associated with 1 phenotype. Biased expression in testis (RPKM 3.3), bone marrow (RPKM 2.4) and 8 other tissues.

Summary

This gene encodes a protein that is likely to function in progression of meiosis. A similar protein in mouse plays a role in gametogenesis in both sexes. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

M1AP Products(4)

mRNA	Protein	Name
NM_001281295.2	NP_001268224.1	meiosis 1 arrest protein isoform 2
NM_001281296.2	NP_001268225.1	meiosis 1 arrest protein isoform 3
NM_001321739.2	NP_001308668.1	meiosis 1 arrest protein isoform 1
NM_138804.5	NP_620159.2	meiosis 1 arrest protein isoform 1

Protein Preferred Names

Protein Names

meiosis 1 arrest protein

meiosis 1 arresting protein

Related Diseases

Diseases

Alias

Spermatogenic Failure 48

SPGF48

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Infertility

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07936	M1AP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	M1AP	MGD	MGI:1315200
Canis familiaris	M1AP	VGNC	VGNC:42907
Bos taurus	M1AP	VGNC	VGNC:31124
Rattus norvegicus	M1AP	RGD	RGD:1563842
Felis catus	M1AP	VGNC	VGNC:63355
Macaca mulatta	M1AP	VGNC	VGNC:74354
Others	M1AP	NCBI