VEGFR-2-IN-5 hydrochloride

Name: VEGFR-2-IN-5 hydrochloride
Brand: MedChemExpress
SKU: HY-18625A
Rating: 4.5 (1 reviews)

Cat. No.: HY-18625A Pureza: 99.51%: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
Technical Support

VEGFR-2-IN-5 hydrochloride is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 69.

Para uso exclusivo en investigación. No vendemos a pacientes.

VEGFR-2-IN-5 hydrochloride Estructura química

No. CAS : 2700435-52-3

Tamaño	Stock	Cantidad

Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

or Consulta para venta a granel

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of VEGFR-2-IN-5 hydrochloride:

VEGFR-2-IN-5 Obtener un presupuesto

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas VEGFR:

Ver todas las isoformas

VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

VEGFR-2-IN-5 hydrochloride is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 69^[1].

IC₅₀ & Target

VEGFR2^[1]

Peso molecular

400.91

Fòrmula

C₁₉H₂₅ClN₈

No. CAS

2700435-52-3

Appearance

Solid

Color

Off-white to light yellow

SMILES

NCCCNC1=CC=C(NC2=NC=CC(NC3=NNC(C4CC4)=C3)=N2)C=C1.[H]Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvente y solubilidad

In Vitro:

DMSO : 230 mg/mL (573.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 100 mg/mL (249.43 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4943 mL	12.4716 mL	24.9433 mL
5 mM	0.4989 mL	2.4943 mL	4.9887 mL
10 mM	0.2494 mL	1.2472 mL	2.4943 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 99.51%

Select Batch:

Ficha de datos (265 KB) SDS (252 KB)

COA (244 KB) LCMS (104 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Gary Johnson, et al. Multiplexed kinase inhibitor beads and uses thereof. WO2013055780A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	2.4943 mL	12.4716 mL	24.9433 mL	62.3581 mL
	5 mM	0.4989 mL	2.4943 mL	4.9887 mL	12.4716 mL
	10 mM	0.2494 mL	1.2472 mL	2.4943 mL	6.2358 mL
	15 mM	0.1663 mL	0.8314 mL	1.6629 mL	4.1572 mL
	20 mM	0.1247 mL	0.6236 mL	1.2472 mL	3.1179 mL
	25 mM	0.0998 mL	0.4989 mL	0.9977 mL	2.4943 mL
	30 mM	0.0831 mL	0.4157 mL	0.8314 mL	2.0786 mL
	40 mM	0.0624 mL	0.3118 mL	0.6236 mL	1.5590 mL
	50 mM	0.0499 mL	0.2494 mL	0.4989 mL	1.2472 mL
	60 mM	0.0416 mL	0.2079 mL	0.4157 mL	1.0393 mL
	80 mM	0.0312 mL	0.1559 mL	0.3118 mL	0.7795 mL
	100 mM	0.0249 mL	0.1247 mL	0.2494 mL	0.6236 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.