VEGFR-2-IN-5
VEGFR-2-IN-5 is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 69.
For research use only. We do not sell to patients.
- CAS No.: 1430089-64-7
- Formula: C19H24N8
- Molecular Weight:364.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
More
Biological Activity
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VEGFR2 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
9110 nM
Compound: CICAMPA-04
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Cytotoxicity against human BT-474 cells incubated for 48 hrs by CCK-8 reagent microplate reader assay
Cytotoxicity against human BT-474 cells incubated for 48 hrs by CCK-8 reagent microplate reader assay
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[PMID: 36827953] |
Chemical Information
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CAS No. 1430089-64-7
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Appearance Solid
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Molecular Weight 364.45
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Formula C19H24N8
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Color White to gray
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SMILES
NCCCNC1=CC=C(NC2=NC=CC(NC3=NNC(C4CC4)=C3)=N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 46 mg/mL (126.22 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (135 KB)
- English - EN (135 KB)
- Français - FR (135 KB)
- Deutsch - DE (135 KB)
- Norwegian - NO (135 KB)
- Español - ES (135 KB)
- Swedish - SV (135 KB)
- Italian - IT (135 KB)
- Korean - KR (135 KB)
- Portuguese - PT (135 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7439 mL | 13.7193 mL | 27.4386 mL | 68.5965 mL |
| 5 mM | 0.5488 mL | 2.7439 mL | 5.4877 mL | 13.7193 mL | |
| 10 mM | 0.2744 mL | 1.3719 mL | 2.7439 mL | 6.8597 mL | |
| 15 mM | 0.1829 mL | 0.9146 mL | 1.8292 mL | 4.5731 mL | |
| 20 mM | 0.1372 mL | 0.6860 mL | 1.3719 mL | 3.4298 mL | |
| 25 mM | 0.1098 mL | 0.5488 mL | 1.0975 mL | 2.7439 mL | |
| 30 mM | 0.0915 mL | 0.4573 mL | 0.9146 mL | 2.2866 mL | |
| 40 mM | 0.0686 mL | 0.3430 mL | 0.6860 mL | 1.7149 mL | |
| 50 mM | 0.0549 mL | 0.2744 mL | 0.5488 mL | 1.3719 mL | |
| 60 mM | 0.0457 mL | 0.2287 mL | 0.4573 mL | 1.1433 mL | |
| 80 mM | 0.0343 mL | 0.1715 mL | 0.3430 mL | 0.8575 mL | |
| 100 mM | 0.0274 mL | 0.1372 mL | 0.2744 mL | 0.6860 mL |
VEGFR-2-IN-5 Related Classifications
HY-18625 Related Classifications
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