XD23

Cat. No.: HY-162970: Data Sheet Handling Instructions
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XD23 is a potent osteosarcoma inhibitor that works by downregulating DKK1 and activating the WNT/β-catenin signaling pathway.

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XD23 화학구조

CAS No. : 2806007-82-7

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50 mg		견적 받기
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250 mg		견적 받기
Other size		견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

XD23 is a potent osteosarcoma inhibitor that works by downregulating DKK1 and activating the WNT/β-catenin signaling pathway.

Cellular Effect

Cell Line	Type	Value	Description	References
A-375	IC₅₀	5.2 μM Compound: 14m	Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
MCF7	IC₅₀	3.15 μM Compound: 14m	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
SK-HEP1	IC₅₀	2.04 μM Compound: 14m	Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
SK-MEL-2	IC₅₀	4.79 μM Compound: 14m	Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]

분자량

471.94

화학식

C₂₂H₂₆ClN₇O₃

CAS No.

2806007-82-7

SMILES

ClC1=CC=CC(NC(CNC2=CC(N3CCN(C)CC3)=NC(N(C)C(N4C)=O)=C2C4=O)=O)=C1

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. https://www.cell.com/iscience/fulltext/S2589-0042(24)01983-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004224019837%3Fshowall%3Dtrue

XD23 Related Classifications

몰농도 계산기
농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XD232806007-82-7XD 23XD-23WntInhibitorinhibitorinhibit

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XD23

XD23 Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Wnt Isoform Specific Products:

Biological Activity

순도&문서

References

고객리뷰

XD23 Related Classifications

몰농도 계산기

농도 희석 계산기